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ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients with Severe Sepsis

The primary objective of this study is to demonstrate that eritoran tetrasodium treatment of patients with severe sepsis results in a reduction in 28-day all-cause mortality.The secondary objectives are to confirm eritoran*s safety profile, and to…

A, randomised, double-Blind, placebo-controlled pilot study with ibuprofen to implement the Post Surgical Dental Pain Model at the Kendle Clinical Pharmacology Unit in cooperation with Departments of Oral and Maxillofacial Surgery

Ibuprofen is a registered drug and belongs to the group of non-steroid inflammation inhibiting drugs. Those drugs inhibit inflammation, are sedative and fever reducing.Ibuprofen is used in pain after dental or mouth chirurgy and after other…

Effectiveness of an Active Lifestyle Promotion Program for Patients with Parkinson*s disease; The ParkFit study

First aim of the study is to investigate whether a physical activity promotion program will result in a improvement in physical activity in sedentary patients with PD. Furthermore, the related health benefits will be analysed.

A randomised controlled trial on the effectiveness of post-exposure prophylaxis (PEP) with oseltamivir in preventing influenza transmission in nursing home units

If proven (cost)effective, without inducing antivral resistance, oseltamivir could have considerable benefits in this setting, although constraints relating to implementation need to be addressed as well. If not (cost)effective if this fragile…

GRACE (Genomics to combat Resistance against Antibiotics in Community-acquired LRTI in Europe).Workpackage 10: Antibiotic Trial One

The aim is to understand which individuals benefit from antibiotics.