23 results
The effects of intravenous TRH administration on brown adipose tissue activity in healthy, lean men.
To investigate whether BAT tissue can be activated by intravenous administration of TRH. Secondary objectives are to determine whether intravenous TRH increases the degree of cardiovascular sympathetic stimulation and the response of skin…
We hypothesize that perioperative ketamine will reduce cognitive decline in postoperative patients, in line with its analgesic and anti-inflammatory properties. There are no previous data available on the effect of ketamine on postoperative…
1) To investigate the effect of atomoxetine on resting-state fMRI measures of network functional connectivity.2) To assess the effect of atomoxetine on several task performance variables, that are hypothesized to reflect tonic LC-NE activity.3) To…
Aim of the study is to evaluate the effectiveness and cost-effectiveness of a positivity training based on attention bias modification as waitlist-intervention for adult outpatients with a major depressive disorder.
Objective: This study will investigate if AIM can be trained among people with chronic anger management processes. According to the AIM model, repeating avoidance responses to threatening stimuli may reduce aggressive impulses within this population…
The aim of the study is: to investigate the effect of DCS on the physiological and subjective correlates reflecting conditioned sexual response and subsequent extinction thereof. Hypothesis: We hypothesize that administration of DCS after an…
The current study aims to investigate the effects of catecholamine modulation by methylphenidate during initial stages of consolidation on memory retention and the underlying neural correlates of memory retrieval.
The primary objective of this study is to establish a causal role of the alpha band oscillations in lateralized parieto-occipital areas during spatial updating with whole-body translation using online transcranial alternating current stimulation (…
To enhance learning by entraining theta oscillations in the frontal cortex using transcranial alternating current stimulation
This study will investigate the counter impulse hypothesis. According to the counter-impulse hypothesis, avoidance motivation counters aggressive impulses. Consequently, this regulatory impact should be especially effective when people*s aggressive…
The main goal of the study is to investigate if small amounts of dopamine could influence engagement during reading, comprehension of the story and vocabulary learning and to investigate if the effect of dopamine is different for carriers of the…
Primary objective is to evaluate the use of deep muscle relaxation versus on indication only on surgical and anesthesia conditions in patients for endoscopic esophageal resection.Secondary objective is to evaluate the (hypothetical) dose of…
Primary objective:- To identify the psychological mechanisms via which testosterone modulates value-based decision making, such as testosterone's effects on risk-taking levels, impulsivity and self-control in intertemporal choice, and social…
To record all reactions of healthy volunteers induced by the use of a homeopathic medicine and placebo.
1) To determine whether vaccination with yellow fever results in a higher cytokine response upon restimulation in vitro with non-related infectious pathogens, compared to the response before the vaccination.2) To determine whether BCG vaccination…
The study consists of two phases. In the first phase, we aim to investigate whether the dopamine receptor D4 (DRD4) genotype confers differential susceptibility to the effects of early life stress on empathy and prosocial behavior more generally in…
First, we want to examine whether a CBM training aimed at inducing positive appraisal style (positive CBM-app) can alter dysfunctional appraisal styles in PTSD patients. Second, we want to examine whether this CBM-app training has an effect on PTSD…
We aim to assess the neurocognitive mechanisms of tyrosine supplementation in older adults during different forms of cognitive control depending on the prefrontal cortex: working memory, reactive and proactive response inhibition, and effort…
The properties of CBD, namely potential effects on variables pertaining to fear extinction and potentially on fear retention/reinstatement while having non of the problematic side-effects found in Δ9-THC, make CBD plausibly preferential over Δ9-THC…
Primary Objective: to ascertain whether tVNS affect performance (as measured by modulation of reaction times and/or error rates) in two cognitive tasks designed to examine PES and PIA, as well as specific components of pupillary response that will…