349 results
The main objective of this study is to investigate the effect of cerebellar tDCS on impulsivity in healthy adults.
Aim of this pilot study is to determine which intervention groups are feasible in a larger trial which aims to a compare postoperative pain and complication rates in moderate versus deep neuromuscular blockade, and normal versus low intra-abdominal…
To assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have an Alzheimer*s disease-causing mutation by determining if treatment with the study drug slows the rate of progression…
To study the effect size of FMT after a 3 weeks course of budesonide as induction therapy in patients with active ulcerative colitis despite previous therapy. The purpose of the pre-treatment is to reduce active inflammation prior to donor feces…
PRP injections are efficacious for symptom reduction and functional improvement compared to placebo injections in the treatment of ankle (talocrural) OA.
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
In the proposed study we will investigate the effect
the foreign language training boosts cognitive flexibility and affects its neural underpinnings, which adds to cognitive reserve. The increase in cognitive flexibility is hypothesized to influence the experience of subjective cognitive decline.…
Onlay and sublay mesh reinforcement after midline laparotomies in patients with an increased risk for the development of incisional hernias (IHs) resulted in less IHs compared to patients that received the conventional closure technique at two years…
Recurrent respiratory tract infections (RTIs) affect 15-20% of children aged 0-5 years and cause high disease burden, frequent doctor visits and are one of the main reasons for hospital admission in childhood. Despite the common use of co-…
Infants’ growth when consuming hydrolysate-based formula is similar to growth when consuming a control formula with intact protein.
We hypothesize that cardiac output rather than blood pressure is essential for adequate cerebral perfusion during and after cerebral revascularization.
The primary hypothesis is that preconscious attention bias modification (ABM) training towards and away from pictorial itch stimuli results in altered preconscious attention for pictorial itch stimuli. Secondarily, it will be explored whether…
The present study explores the dose-response relationship in LSD-induced subjective and cognitive effects using small doses of LSD (5, 10, and 20 µg) compared to placebo. The study hypothesis is that higher doses of LSD will be associated with…
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
Our hypothesis is that preservation of the pectoral fascia may lead to a decreased seroma formation when compared to fascia removal, and has a beneficial effect on breast reconstructive surgery.