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An interventional, prospective IVD device study for the testing of DNA extracted from tumor tissue biopsy samples from adult participants with metastatic Non-Small Cell Lung Cancer (NSCLC) for potential inclusion in the MSD Phase 3 clinical trial (Protocol No MK-1084-004) to demonstrate clinical performance of the therascreen® KRAS RGQ PCR Kit.

To utilize the therascreen KRAS RGQ PCR Kit (KRAS Kit) as a screening test to identify KRAS G12C mutations in newly diagnosed metastatic NSCLC participants and thereby determine eligibility for enrolment into the Phase 3 clinical study (MK-1084-004…

Evaluation of the additional effect of continuous ultrasound bladder monitoring in urotherapy for children with functional daytime urinary incontinence. The SENS-U trial

To evaluate cost effectiviness of the SENS-U (continuous ultrasonic bladder monitoring) in urotherapy for children with functional daytime urinary incontinence.

Gut-brain health effects of PREbiotics in older adults with suspected COgnitive DEcline: the PRECODE study

The primary objective of this study is to investigate the effect of 26 weeks of supplementation with three different dietary fibres (chicory inulin, resistant dextrin, and seaweed polysaccharide) compared to a placebo (maltodextrin) on microbiota…

The effect of algae oil supplements on functional immune response and bioavailability of lipids in blood, a pilot study

The primary objective is to estimate functional immune response in isolated peripheral blood mononuclear cells (PBMCs; ratio of pro-inflammatory; i.e. PGE2, IL-1β, IL-6, IL-8, IFN*, TNFα, CCL2 and CCL5, and anti-inflammatory markers; i.e., IL-4 and…

Targeted PRECIsion NUTrition strategy to prevent chronic metabolic diseases

Our study aims to identify unique Metabotypes among individuals with overweight at risk of T2DM and assess their response to a 1-year precision dietary macronutrient modulation. The objective is to provide proof-of-concept that this approach…