840 results
The aim of this study is to use diaphragmatic muscle activity measurements in premature neonates to develop an algorithm that can quickly identify that the patient has apnoea and then classify it by type (obstructive, central or mixed). This could…
To assess the concurrent validity of the FastFocus* Vital Sign Monitoring System classification algorithm that discriminates between lying, sitting/standing, and walking activities, and detects number of walking steps in hospitalised patients under…
In this project we aim to investigate whether we can precisely measure the changes in fermentation gas patterns after supplementation of a complex fibre mixture over a 36-hour period in both lean normoglycemic and insulin resistant and/or…
The primary aim of this study is to investigate the feasibility, acceptability and user-friendliness of implementing PM+ in Dutch prisons. This is a version of PM+ that is specifically adapted to the prisoner population and prison context. The…
To test whether the use of magnetic localization seeds causes image artifacts on CEM.
Primary Objective: to assess the feasibility of the use of BabyCheck combined with standard PO for infants < six months of age presented at the emergency GP post. Secondary Objective(s): 1. To assess the sensitivity and specificity of the…
Our objective is to compare the efficacy of early chest tube removal combined with single-shot PVB versus standard treatment (chest tube for at least 3 days and thoracic epidural analgesia (TEA)) after surgery for PSP. Efficacy is defined as proving…
To evaluate the efficacy and safety of tucatinib in combination with trastuzumab and mFOLFOX6 in comparison to mFOLFOX6 given with or without either bevacizumab or cetuximab as first-line (1L) treatment in adults with HER2 positive (HER2+)…
The main objective of this study is to investigate whether there are differences in the way factors such as learning progress (LP) maximization and prediction error (PE) minimization drive the exploratory behavior of children with autism compared to…
This study has been transitioned to CTIS with ID 2024-515832-59-00 check the CTIS register for the current data. To assess the long-term safety and tolerability of treatment with efgartigimod PH20 SC in participants with BP
An Open-label Extension Study of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
To evaluate the long-term safety and tolerability of inhaled treprostinil in subjects with IPF.
The objective of the ADVANTAGE AF Study is to establish the safety and effectiveness of the FARAPULSE Pulsed Field Ablation System (FARAPULSE PFA System) for treatment of drug resistant, symptomatic persistent atrial fibrillation (PersAF).
Current literature indicates that one week of cast or brace immobilisation is safe, however, no level one evidence is available. This trial aims to compare one week of brace immobilisation with three weeks of cast immobilisation in non- or minimally…
The current research project aims to improve the care of CABG patients, by a redefinition of PMI. In this research proposal, we focus on the diagnostic and clinical relevance of postoperative biomarker increases and will determine the association…
The primary objective is to develop and validate non-invasive portal pressure measurement by MRI in patients with end-stage liverdisease (ESLD).
In this proposal, we therefore aim to characterize in detail the cutaneous B cell response in patients with isolated CLE (CLE only) and patients with systemic and cutaneous disease (SLE/CLE). Primary Objectives: 1. Characterize autoreactive B cells…
To investigate the effect of implementing continuous antepartum eCTG monitoring at the OHC, on perinatal and maternal outcomes and obstetric care
The primary objective is to investigate if a very short-course of antibiotics for cholangitis after adequate drainage is non-inferior with respect to clinical cure in comparison with a standard course of antibiotics.
To assess safety and performance of the LithiX Coronary HCIVLC to treat moderately to severely calcified coronary artery lesions by calcium fragmentation utilizing Hertzian contact stress from LithiX HCIVLC.