349 results
The hypothesis is that the prevalence of heart failure is underestimated in Dutch nursing homes. In addition it is hypothesized that residents with heart failure experience a lower quality of life, have a higher degree of care dependency and have…
Our hypothesis is that the iron status in young healthy children from the Netherlands might be insufficient.
The postprandial plasma triglyceride levels will be different in breastfed compared to formula fed infants.
Intraoperative cholangiography with the Kumar clamp is faster and easier than with the Olsen clamp.
The addition of regionale hyperthermia to treatment with intravesical chemotherapy with mitomycin C is feasible and not toxic.
To evaluate the effect of 15 minutes of immobilisation after IUI on pregnancy rate in couples with unexplained, cervical factor or male subfertility.
Postprandial hyperglycemia has a negative effect on aortic elasticity in patients with impaired fasting glucose versus matched controls.
The most important problem after kidney transplantation is the occurrence of chronic interstitial fibrosis (IF) and tubular atrophy (TA), which leads to graft loss. Tacrolimus induced nephrotoxicity importantly contributes to the development of IF/…
To determine the MTD of pazopanib in combination with docetaxel dosed according to two regimens (3-weekly infusion[Arm A]; weekly infusion [Arm B]), in subjects with solid malignancies.
The expectation is that fear of childbirth and additional pain are important reasons for choosing analgesia, or at least influence the choice. An expected reason for not choosing analgesia is that it could be detrimental for the (unborn) child. It…
A reduction-to-quit smoking intervention for COPD patients, that combines behavioural counselling with nicotine replacement therapy (NRT), leads to an increase in sustained abstinence after 18 months, compared to a brief self-help smoking reduction…
Electrical stimulation on the foot and lower leg will increase the blood flow and thereby the amount of oxygen to the skin. Our overall hypothesis is that this will help to reduce the risk of decubitus on the heel. The specific hypothesis for this…
A randomized controlled trial to compare the following strategies: two IVM-ICSI cycles or one COH-IVF/ICSI cycle. These strategies are expected to have comparable outcomes for ongoing pregnancy rates and direct costs (treatment costs). IVM is…
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…
The culturally adapted version of the web-based guided self-help intervention Alles Onder Controle(in Dutch and Turkish) will reduce symptoms of depression among Turkish adults living in the Netherlands.
In our view a proper functioning working memory (WM) is not only important for cognitive processes as language, memory etc. (i.e. ‘cold’ cognitive information), but is also essential for successfully navigating in the social world (i.e. ‘hot’…
The proposed four-way randomised controlled trial evaluates the cost-effectiveness the current ruling widespread Royal Dutch Physiotherapy Association (KNGF) guideline (i.e. this guideline is being used by physical therapists, (sports) physicians,…
Fluorescent near-infrared imaging can accurately detect pancreatic cancer non-invasively during a whipple procedure.
Early detection of problems and adequate coaching of frail elderly people is crucial to prevent unnecessary loss of function, decrease in quality of life, and even death in old age. This is especially true for frail elderly people who are admitted…
In the present study we will investigate the efficacy of Lybrido and Lybridos in one group of subjects with FSD using SSRIs in the laboratory and in the domestic setting of these subjects. We will measure subjective, physiological and…