63 results
treatment of overweight persons with insulinresistance with a low dose metformine add to yoghurt The early reduce of glucose especially the postprandial will hopefully decrease this process. This reduce of the glucose only needs to be 1 mmol and we…
Investigate the effects of levocetirizine, diphenhydramine and placebo on cognitive and psychomotor functioning during controlled simulated diving in a recompression chamber in professional navy divers at 10 mt (2 bar) and 30 mt (4 bar).
The aim of the study is to evaluate the safety of the Flex catheter and the effect of the renal denervation on blood pressure.
The primary objective is to study whether treatment with the mTOR inhibitor Everolimus results in an objectable change in phosphorylation of the selected downstream effectors 4eBP1 and p70S6K in human prostate cancer biopsies. A secondary objective…
ObjectiveInventory of the support and willingness of the visitors of the temples to participate. This study should be beneficiary in the development of a preventive program, focusing on depression. The primary outcome of this randomised trial is:…
To identify intraarticular parameters related to the initiation and course of development of articular cartilage lesions after knee trauma.
Primary objective: to compare changes in endothelial function in patients with obesity related hypertension after 8 weeks of treatment with aliskiren, moxonidine and HCTZ.Secondary objectives: to compare changes in the following parameters in…
(1) How accurately do the TVS-CMD items reflect clinically relevant symptoms? (2) What is the concurrent and discriminant validity of the TVS-CMD? (3) How can the scoring system of the TVS-CMD be optimised?
2.1 Primary objectiveTo compare the wear rate 24 months after THA of HXLPE stabilized with vitamin E versus conventional UHMWPE for total joint arthroplasty.2.2 Secondary objectives1. To compare the wear rate at 3,12 and 24 months after THA between…
1. Is KJD clinically non-inferior to current surgical techniques (HTO and TKP)?2. Is KJD superior to HTO in actual structural repair of cartilage?3. Is KJD cost-effective in the long-term compared to HTO and TKP?
To determine safety and efficacy of oocyte vitrification.
This pilot clinical trial has been designed to evaluate the safety and performance of the INSTRUCT scaffold, and to collect preliminary efficacy data
Primary goal:To investigate whether specific plaque characteristics are associated with ischemic lesions, especially (clinically silent) cerebral micro-infarcts, we will perform preoperative high resolution 3 and 7 Tesla MR plaque imaging in…
The primary objective is a) to study the occurrence of recurrent wheezing following hospitalisation for severe RSV LRTD, and to study the differences in occurrence between ventilated and non-ventilated infants, and ) to study differences in lung…
Research of lung function and exercise capacity in late preterms (32-36 weeks gestation) in comparison with term born controls of 8 years
To evaluate whether preventive treament with haloperidol lowers the risk for delirium in stroke patients with an increased risk for delirium.
Our aim of the study is investigate IL-7, TSLP and CD30(L) expression in SLE patients en healthy controls to better understand pathogenesis and to find a biomarker that is related to disease activity.
The goal of the proposed study is to build knowledge about the effect of Naltrexone in a regular sample of cannabis addicts in a mid-size town. To accomplish this, we propose to: a) do a double blind randomized controlled trial with Naltrexone in…
To compare an unexplained chronic fatigue group and a healthy control group on: 1) immune parameters (hs-CRP), 2) several subjective (self report) measures of non-specific symptoms of immune activity, 3) several objective measures of non-specific…
Primary Objectives:1. To compare the magnitude of baseline (or intrinsic) platelet reactivity between T2DM patients and healthy volunteers using multiple platelet function assays 2. To compare the magnitude of baseline (or intrinsic) platelet…