58 results
1. the primary objective of this study is to examen the incidence and prevalence of PTSDand depression in pre-eclampsia patients after delivery2. a secondary objective is to identify risk factors during pregnancy, durante partu and postpartum…
Firstly, to study the reduction in sick-leave time achieved by the treatment protocol. Secondly to study the quality of life in the patients treated in the fast-track protocol, to study the reduction in societal costs and to stdy the efficacy of a…
Objectives: The objective of the study is to observe the sorbitol clearance and compare this to ICG clearance in different circumstances of normal and compromised liver blood flow.
Primary objectives:1a. To determine the severity and course of obstructive sleep apnea in children with congenital mandibular hypoplasia (both isolated and syndromal).1b. To determine the growth pattern of the lower face in relation to the upper…
The primary objective of the study is to demonstrate the reduction of low-density lipoprotein (LDL) cholesterol (LDL-C) by REGN727 in comparison with ezetimibe (EZE) 10 mg PO QD after 24 weeks in patients with primary hypercholesterolemia (…
Primairy goal of the study is to treat anxiety disorder patients more cost-effectively (shorter treatments with equal treatment results).
Primary Objective: 1. An explorative study to investigate whether a change in pain complaints or depressive symptoms can be predicted using baseline EEG/ERP measures derived from vulnerability experiments.Secondary Objective(s):1. To explore changes…
The primary objective of this study is to test safety and performance of the APD Perfusion Measurement Catheter & Monitor for the measurement of gut perfusion in humans. The secondary objectives of this study are to assess the normal values…
The purpose of the study is to investigate the effect of endothelial cells in TEG-cups compared to plain (no endothelial cells) cups on coagulation and fibrinolysis.
Considering the high prevalence of smoking and tobacco related deaths, knowledge about the appealing function (attractiveness) of tobacco additives is highly significant, because they promote the initiation of smoking. This part of the investigation…
The first objective is to examine the impact of 4-month walking training on physical fitness, insulin resistance and cardiovascular risks in T2DM and their controls and to assess whether these effects are preserved 3 months after cessation of the…
Previous investigations in our lab have provided insight in the requirements for development of such a system and shown the feasibility of the paradigm (Blokland et al., 2011). We have been able to optimize the settings of our proposed system to…
Primary objective: To create diagnostic and treatment tools for navigation ability in stroke patients, that can be used in clinical practice.Secondary objective: To increase knowledge about the cognitive structure and neuroanatomical correlates of…
The aim of the study is to measure whether there is a difference in LDL cholesterol levels or the 24 hour ambulatory blood pressure in individuals at high risk of cardiovascular disease when the polypill is taken in the morning compared with the…
The primary objective of this study is to assess the effect of individualizing the growth hormone dose versus standard treatment with 1 mg/m2/day on adult height and the first and five year growth response. Secondly, we want to assess the long term…
To compare in a randomized controlled trail (RCT) the risk of neonatal hyperbilirubinaemia between neonates treated with CFT and amoxicillin-clavulanic acid (augmentin, AUGM) combination versus neonates treated with the aminoglycoside, tobramycin (…
Our aim is to optimize treatment for patients with moderate to severe psoriasis by creating evidence for the optimal dose of MTX (on short- and long-term) with the largest disease reduction and the least side effects.
The purpose of this study is to evaluate whether there are differences in duration and intensity at a femoral nerve block with ropivacaine Klaris standard 30ml 0.2% with and without addition of buprenorphine (Temgesic ®) 0.3 mg buprenorphine…
Our aim is to determine the effect of APO* on activity and volume of the hippocampus, a core structure of Alzheimer pathology, at a young age. Specifically, we aim 1) to determine the effects of APOE e4 on hippocampal activation in the young general…
To provide single dose PK/PD dataTo investigate tolerability and safety of dabigatran etexilate solution in children1 to <12 years of age