106 results
Human intestinal biopsies will be used to further develop an in vitro intestinal model. This model will the be used for future research to study the effect of nutreints and drugs on intestinal function. The human biopsies will be compared with…
The primary objective is to evaluate health related QoL under an oral sequential treatment with natural steroid hormones: Duogestan®. The secondary objective is to evaluate the bleeding patterns over a one-year period.
The study will assess the hypothesis that for treating a bifurcation lesion in a coronary artery the combination of a drug eluting balloon and a bare metal stent is non inferior to the standard provisional T-stenting technique using a drug eluting…
To evaluate health related QoL under an oral cyclic treatment with physiological steroid hormones: Duogestan®.
The main objective is to gain insight into the effects of guided imagery on pain, self efficacy and functional status of people with fibromyalgia and into the relationships between these outcome variables.
To assess the prevalence of HIV, hepatitis C and B, and (related) risk behavior among hard drug users in care at Mondriaan carecentre for addiction in Heerlen.
To study potential abnormal functioning of the bile salt-FXR-FGF19 axis in patients with clinically quiescent Crohn*s colitis.
The minimal duration of an effective distraction period has not yet been determined. In the past, two months distraction showed comparable results with three month distraction. In this study, we would like to analyse the effectivity of a one month…
The current study is designed to test the hypothesis that the medulla in transplanted kidneys is still hypoxic at 1 day after transplantation using a non-invasive method: BOLD MRI.By studying two groups a comparison can be made between patients…
To assess the incidence and severity of embolic events during spinal instrumentation surgery with intraoperative transesophageal echocardiography monitoring.
In the current proposal we hypothesize that vulnerability to stress is a non-specific risk factor for developing either schizophrenia or MDD. Increased stress sensitivity is hypothesized to be related to reduced prefrontal functioning, leading to…
The objective of this observational study is the safe introduction of clinical applied IVM in The Netherlands. During this study, the number and quality of the oocytes and embryos will be studied as well as pregnancy development. Emphasis will be on…
Goal of the study is to establish evidence on cognitive biases in a high risk population and on the longitudinal impact of such biases. We hypothesize that CPAD*s show biases in their information processing when compared to control children. We…
The aim of this study is to investigate whether DWIBS may be an appropriate technique for colorectal cancer screening.
Study ObjectiveTo determine whether alprazolam, a registered anxiolytic non-selective benzodiazepine, can reduce the autonomic temperature increase induced with social stress in healthy men. Secondary objectives are to determine whether alprazolam…
To determine exercised-induced bronchoconstriction with an objective and standardized exercise test for infants and young children (3-6 years); to compare resistance and compliance in wheezy children and healthy children before and after exercise-…
To determine the reliability and feasibility of the Nanoduct sweat test system compared to the gold standard tests QPIT and Macroduct.
The main objective is to describe the interactions between physical sensory stimulations and high-level prior assumptions that give rise to visual perception. In our secondary objective, we will advance novel model-based neuroimaging methods by…
: The primary objective of this study is to demonstrate non-inferiority by pharmacodynamic (PD) analysis of the prasugrel 5-mg maintenance dose (MD) in aspirin-treated subjects >=75 years of age with stable coronary artery disease (CAD)…
To assess the prevalence of HIV, hepatitis C and B, and (related) risk behavior among hard drug users in care at Mondriaan carecentre for addiction in Heerlen.