105 results
1. the primary objective of this study is to examen the incidence and prevalence of PTSDand depression in pre-eclampsia patients after delivery2. a secondary objective is to identify risk factors during pregnancy, durante partu and postpartum…
Firstly, to study the reduction in sick-leave time achieved by the treatment protocol. Secondly to study the quality of life in the patients treated in the fast-track protocol, to study the reduction in societal costs and to stdy the efficacy of a…
Objectives: The objective of the study is to observe the sorbitol clearance and compare this to ICG clearance in different circumstances of normal and compromised liver blood flow.
Primary objectives:1a. To determine the severity and course of obstructive sleep apnea in children with congenital mandibular hypoplasia (both isolated and syndromal).1b. To determine the growth pattern of the lower face in relation to the upper…
The primary objective of the study is to demonstrate the reduction of low-density lipoprotein (LDL) cholesterol (LDL-C) by REGN727 in comparison with ezetimibe (EZE) 10 mg PO QD after 24 weeks in patients with primary hypercholesterolemia (…
Primary Objective:The primary objective in the current trial is to use graph theory to examine how the organization of the functional brain network may be altered by the administration of methylphenidate. The main question we intend to answer in…
Clarify the effect of 5T polymorphism with or without another CF causing mutation on the other allele, on the CFTR function.
To compare the effect of IT dexamethasone versus IT gentamicin on number and severity vertigo attacks.To compare the effects of IT dexamethasone with IT gentamicin on hearing function, functional level scale and aural fullness.
Primairy goal of the study is to treat anxiety disorder patients more cost-effectively (shorter treatments with equal treatment results).
Primary Objective: 1. An explorative study to investigate whether a change in pain complaints or depressive symptoms can be predicted using baseline EEG/ERP measures derived from vulnerability experiments.Secondary Objective(s):1. To explore changes…
The primary objective of this study is to test safety and performance of the APD Perfusion Measurement Catheter & Monitor for the measurement of gut perfusion in humans. The secondary objectives of this study are to assess the normal values…
The purpose of the study is to investigate the effect of endothelial cells in TEG-cups compared to plain (no endothelial cells) cups on coagulation and fibrinolysis.
Considering the high prevalence of smoking and tobacco related deaths, knowledge about the appealing function (attractiveness) of tobacco additives is highly significant, because they promote the initiation of smoking. This part of the investigation…
The first objective is to examine the impact of 4-month walking training on physical fitness, insulin resistance and cardiovascular risks in T2DM and their controls and to assess whether these effects are preserved 3 months after cessation of the…
Previous investigations in our lab have provided insight in the requirements for development of such a system and shown the feasibility of the paradigm (Blokland et al., 2011). We have been able to optimize the settings of our proposed system to…
Primary objective: To create diagnostic and treatment tools for navigation ability in stroke patients, that can be used in clinical practice.Secondary objective: To increase knowledge about the cognitive structure and neuroanatomical correlates of…
The aim of the study is to measure whether there is a difference in LDL cholesterol levels or the 24 hour ambulatory blood pressure in individuals at high risk of cardiovascular disease when the polypill is taken in the morning compared with the…
Evaluation of therapeutic safety and clinical efficacy of MSC transplantation in septic shock.
The primary objective of this study is to assess the effect of individualizing the growth hormone dose versus standard treatment with 1 mg/m2/day on adult height and the first and five year growth response. Secondly, we want to assess the long term…
To compare in a randomized controlled trail (RCT) the risk of neonatal hyperbilirubinaemia between neonates treated with CFT and amoxicillin-clavulanic acid (augmentin, AUGM) combination versus neonates treated with the aminoglycoside, tobramycin (…