15 results
To evaluate the acceptability and effectiveness of a deepfake victim-perpetrator confrontation in young adults with sexual violence-related PTSD.
This study has been transitioned to CTIS with ID 2024-520305-39-00 check the CTIS register for the current data. Primary objective: to evaluate the efficacy of LSD 25µg every 3 days for 3 weeks in cCH. Additional objectives:- To evaluate the safety…
Primary Objective: • To determine the clinical Progression Free Survival (cPFS) in our study cohort of patients with mCRPC and 68Ga-PSMA-PET/CT selected bone-only disease (PET-bone only group). The cPFS will be compared to the cPFS of patients with…
The primary objective is to investigate the concordance between the Endosign test and EGD by an expert endoscopist for detecting dysplasia and/or EAC in a high-risk category of ULSBE patients. Secondary objectives are to determine the acceptability…
The main objective of this study is to establish a controlled human infection model for Chikungunyausing the VLA1553 vaccine.Primary objectives:- To assess the infection rate induced by a single administration of the VLA1553 vaccine- To assess the…
The primary objective is to perform a clinical validation of the analytical method for dried blood spot microsampling of cabozantinib, pazopanib, sunitinib, Lenvatinib, nivolumab, ipilimumab, pembrolizumab, atezolizumab or bevacizumab. The secondary…
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
To assess the practical usability of our DRS probes for the detection of positive resection margins in colorectal cancer surgery - specifically whether they can be used in the confined surgical workfield in the lower pelvis - as well as the…
The main objective of this study is to assess the feasibility, safety and (cost-)effectiveness of the HOME-ART intervention in comparison to regular hospital admission in patients with CA-ARTI.
The aim of this study is to investigate whether the transfer of antibodies from mother to infant is less effective in infants with intrauterine growth restriction (FGR) compared to term-born infants without intrauterine growth restriction or who are…
This study aims to evaluate and compare the long-term outcomes of tissue-level and bone-level single implants in the posterior region of the mandible or maxilla in patients with adequate bone for implant placement, with or without prior bone…
The aim of this trial is to investigate the safety and efficacy of an adaptive anastomosis using the C-REX RectoAid Cath following elective anterior resection for sigmoid or proximal rectal cancer, or premalignant lesions not amenable tot endoscopic…
To investigate whether TLND can be safely omitted in patients with macroscopic resectable stage III (B/C/D) melanoma achieving an MPR within the ILN upon neoadjuvant treatment with nivolumab in combination with ipilimumab.
The main (primary) objective is to study the influence of sex on the pharmacokinetics (PK) of metoprolol in patients after CABG with heart valve surgery and patients with a STEMI/NSTEMI who are prescribed a standard dosage of metoprolol as part of…