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A randomized placebo-controlled trial comparing cyclosporine plus steroids with or without Myfortic as primary treatment for extensive chronic graft-versus host disease

Approved WMORecruitment stopped

To improve response rate of primary treatment of extensive chronic GvHD with the addition of MPA to the reference treatment CsA+PDN (comparator)Primary ObjectiveTo improve remission rates with cyclosporine A+ prednisone + Myfortic® (CsA+PDN+MPA)…

A Prospective, Open-label, Multicenter, Randomized Study to Evaluate the Benefits and Risks of
Conversion of Existing Adolescent Renal Allograft Recipients Aged 12 to Less Than 18 Years of
Age to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a
Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Approved WMORecruiting

This study has been transitioned to CTIS with ID 2022-501677-39-00 check the CTIS register for the current data. Evaluation of patient and functional graft survival of adolescent renal allograft recipients converted from CNI to belatacept-based…