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Perioperative antibiotic use in the treatment of acute calculous cholecystitis

To demonstrate that extended postoperative antibiotic treatment does not decrease the infectious complication rate in laparoscopic cholecystectomy for acute cholecystitis.

Short-course aminoglycosides as adjunctive treatment in adults with sepsis

The objective of the proposed study is to determine the effectiveness, safety and cost-effectiveness of a strategy of cefuroxime combined with short course treatment with aminoglycosides compared to a strategy of ceftriaxone monotherapy in patients…

Standard versus Pre-emptive Antibiotic Treatment to Reduce the Rate of Infectious Outcomes after Whipple procedure (SPARROW): a multicenter, randomized controlled trial

This study has been transitioned to CTIS with ID 2024-510766-16-00 check the CTIS register for the current data. This trial evaluates the additional value of pre-emptive antibiotic treatment on clinically relevant OSIs in patients undergoing…