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Clonidine Augmentation Treatment in Schizophrenia

The primary aim is to investigate whether six weeks augmentation with clonidine of the antipsychotic treatment will reduce positive and negative symptomatology of treatment resistant schizophrenia patients. Important secondary goals of this project…

The neurobiological basis of bias;
A mechanism implicated in visual spatial attention.

The goal of the current investigation is to test the noradrenergic part of a new model that accounts better for results of pharmacological research. This model states that the cholinergic system underlies disengagement, and that the…

Effectiveness of Clonidine for the treatment of radicular pain: A randomized, double-blind and prospective study. (EFFOC study)

1) To study the effect of Clonidine on lumbar radicular pain with a transforaminal epidural injection after 1 week, 1, 3 and 6 months using a BPI.2) To study the effect of Clonidine on lumbar radicular pain with a transforaminal epidural injection…

The role of alpha2-adrenergic receptors in bone remodeling.

The objective of the study is to investigate the effect of alfa2-adrenoceptors on bone turnover.

The neurobiological basis of bias and disengagement;
Two neurotransmitter mechanisms implicated in visual spatial attention.

The goal of the current investigation is to test a new model that accounts better for results of pharmacological research. This model states that the cholinergic system underlies disengagement, and that the noradrenergic system underlies bias. Two…