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Study to Identify Factors associated with Resilience to Clinical Dementia at Old Age

The main objectives are to understand how clinical markers and biomarkers previously identified in younger and older AD cohorts apply to the extreme elderly (90+ years old) and to identify novel biomarkers linked with resilience to developing…

Multicentre, Open-label, Randomised Study to Assess the Diagnostic Value of Amyloid PET
Imaging in Patients with Subjective Cognitive Decline Plus, Mild Cognitive Impairment, or Dementia
Where Alzheimer*s Disease Is in the Differential Diagnosis (Diagnostic and Patient Management
Study)

This study (AMYPAD Diagnostic and Patient Management Study) will determine in a real-life clinical setting for whom diagnostic amyloid PET imaging is appropriate, when this is best performed, and how the resulting information is influencing…

18F-Flutemetamol PET/MRI for detection of plaque vulnerability in atherosclerosis

To validate 18F-Flutemetamol PET in the evaluation of plaque vulnerability.

AMYPAD Prognostic and Natural History Study (PNHS), an open label, prospective, multicentre, cohort study in individuals without dementia to evaluate the additional value of quantitative amyloid imaging in determining Alzheimer*s Disease (AD) dementia risk

The aim of this study is to evaluate the additional value of quantitative amyloid imaging analysis for modelling and assessing Alzheimer*s Disease (AD) dementia risk in individuals without dementia, compared to a range of existing cognitive, imaging…