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Combined effects of biperiden and acute tryptophan depletion on memory in healthy volunteers: an EEG study

The primary objective is to examine whether a memory impairment as a result of biperiden treatment (cholinergic M1 antagonist) will be increased by acute tryptophan depletion (ATD, a drink that decreases serotonin synthesis). In other words, we will…

Effects of rivastigmine on biperiden-induced memory impairment in healthy adults: an EEG study

The primary objective is to examine whether a memory impairment as a result of biperiden treatment (cholinergic M1 antagonist) can be reversed by rivastigmine (a cholinesterase inhibitor). Secondary, we will assess the effects of biperiden and…