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Pharmacokinetics of new dexamphetamine sustained release tablets and the clinical validation of measuring dexamphetamine in dried blood spots

The main objective of this study is to determine the release profile of the dexamphetamine sustained release tablets in vivo in humans. Depending on the results, the tablets might be candidates for use in the therapy of attention deficit…

A Randomized, Placebo- and Comparator-controlled, Double-blind, Multiple (Ascending)
Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and
Pharmacodynamics of JNJ-54175446 in Healthy Male Subjects

Primary Objectives(1) investigate the safety and tolerability of JNJ-54175446 after multiple consecutive dose administrations;(2) investigate the plasma pharmacokinetics of JNJ-54175446 following multiple dose administration in healthy male subjects…