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The use of Rienso, an ultrasmall superparamagnetic particle of iron-oxide, as a MRI contrast agent to image inflammation in the atherosclerotic plaque.

Approved WMORecruitment stopped

In the current study, we want to demonstrate Rienso uptake in the vessel wall in patients with cardiovascular disease and relate the uptake of Rienso to endothelial permeability.

Ultrasmall superparamagnetic particels of iron oxide (USPIO) enhanced MRI to differentiate between simple steatosis and non-alcoholic steatohepatitis.

Approved WMORecruitment stopped

In the current study we want to evaluate the correlation between hepatic uptake of Rienso and the histological NAFLD activity score (NAS, necroinflammatory grade) in liver biopsy specimens from patients suspected of having NASH. Besides, we want to…