4 results
To compare the effects of various upper extremity positions on the sagittal spinal alignment, to determine which position corresponds the most with the neutral position and to determine which position is the most reliable across repeated…
The main purpose of this trial is to find out if an investigational drug called setmelanotide (RM-493), which mimics MSH, can help control body weight. The efficacy of setmelanotide will be compared to the efficacy of a placebo during 4 to 8 weeks.
Primary:• To evaluate the proportion of patients with obesity with genetic variants in a specific gene in the melanocortin-4 receptor (MC4R) pathway who achieve a clinically meaningful reduction in body weight in response to setmelanotide at the end…
To evaluate the efficacy of setmelanotide on changes in body weight.