4 results
Primary objective: to register and investigate Dutch patients suspect for an inherited platelet function disorder, to assess clinical presentation, bleeding score, treatment, burden of disease and quality of life. Secondary objectives: to…
To demonstrate the ability of using non-invasive 31P-MRS to monitor changes of in vivo markers of mitochondrial function in skeletal and cardiac muscles (i.e., skeletal muscle PCr recovery rate constant and cardiac PCr/ATP ratio)…
Primary objectives: 1.1) To investigate to what extent the different functions of the cerebral microvasculature are impaired in type 1 diabetes; and 1.2) To investigate to what extent the different functions of the cerebral microvasculature are…
To gain insight in the disease mechanisms of IBD, the immune system, gut and oral microbiome, environmental factors, the intestinal mucus barrier, intestinal epithelium, nutritional factors and metabolome will be studied in unaffected siblings of…