387 results
Primary objective of the study is to determine the effect of 2 different treatment strategies of vitamin D supplementation on 25(OH)D3 serum concentration after 12 months of supplementation. Secondary objectives are to determine the effects on the…
To compare standard treatment with intravesical chemotherapy with loco-regional thermo-chemotherapy in patients with an intermediate risk non-muscle invasive urothelial carcinoma of the bladder after complete transurethral resection of the tumour(s…
Primary Objective: To compare peri-implant hard and soft tissue changes as measured on standardized intraoral radiographs and direct digital intraoral scans between the group of single final and and the group of multiple repeated abutment dis/re-…
To investigate whether two newly developed, potato based LOPG drinks with a different osmolarity and volume taken before exercise, differently affect gastric distress after both a short and long term exercise, running performance, and the rate of…
Primary objective:To assess the feasibility of KD in patients with glioblastoma multiforme during standard treatment.Secundary objectives:- To determine number of patients not being able to start protocol treatment (i.e. not able to reach ketosis,…
The aim of this study is to evaluate the analgesic effects of LLLT on maxillary and mandibular block pre-injection sites in patients scheduled for elective third molar removal.
To assess whether treatment with DBS can reduce or resolve TDD and if DBS can induce beneficial or side effects in particular psychiatric and or cognitive symptoms.
To demonstrate efficacy of adjuvant combination chemotherapy in a randomized phase III trial comparing to no further treatment in the medium and high-risk node negative stage I and stage II patients.
Primary goal: mean linear wear of the cross-linked polyethylene F.A.L. cup compared to the mean linear wear of the standard polyethylene F.A.L. cup at 5 years postoperatively. Secondary goals:1. mean linear wear (millimeters/year) at 1 year, 3 years…
In this study, we aim to test the feasibilty, reliability and validity of the MOX-accelerometer in measuring daily physical activity in children with mitochondrial disease.
To investigate the feasibility and efficacy, expressed as percentage funcitoning time and time in target range, respectively, of an automated closed-loop glucose control system based on subcutaneous continuous glucose measurements in critically ill…
The primary objective of this trial is to assess the effectiveness of IG-SBRT in patients with medically inoperable early stage, centrally located NSCLC and in those who are not willing to undergo surgical treatment.The primary measure of…
Primary objectives:- To investigate the long-term outcome after successful treatment (no subretinal fluid on OCT) in the PLACE trial.- To investigate whether a cross-over treatment of half-dose PDT to HSML in cCSC patients who either did not respond…
To investigate whether hyperthermia induces HR-deficiency in cervical tumors and as a feasibility study, secondly to investigate whether it is possible to detect circulating tumor cells before and after hyperthermia.
The Aptus Endosystems STAPLE International Post-Market Registry is intended to expand the clinical knowledge base by including 'real world' subjects. As an active means of data collection, the Registry will serve to address post-production…
The purpose of this investigation is to evaluate the ESPOIR PV in comparison to current valve substitutes within a large prospective multicentre surveillance at 8 leading European Centres for Congenital Cardiothoracic Surgery regarding re-operation…
Objective: Primary objective is to demonstrate non-inferiority of the e-prescription to the use of antidepressants on the short term. Secondary objectives are to assess its effect on long term outcomes, antidepressant use, and to assess its…
The primary objective is to get a first insight what the effect of FSWT and RSWT is on the tendon structure in treating patellar tendinopathy patients and on healthy tendons determined by UTC.The secondary objective is to compare the effect of FSWT…
Determination of prognostic value of intraoperative growth hormone levels on postoperative curation for acromegaly in patients undergoing transsphenoidal resection of pituitary adenoma.
This study aims to improve the first phase of rehabilitation after THA. The primary objective is to analyse the effect of feedback to the patients. The secondary objective is to quantify the weight bearing in the early phase after THA surgery.