90 results
Investigate the effect of FMT from healthy obese donors on objective response rate (ORR according to RECIST criteria) in patients with metastasized or locally advanced NSCLC receiving standard of care first-line immunotherapy with or without…
The primary objective of this study is to compare the mean binocular DCIVA at 66 cm under photopic conditions 3 months after cataract surgery, in a series of patients, who previously underwent myopic laser surgery, bilaterally implanted with the non…
Primary: To describe shoulder function, local fatigue and pain symptoms around the shoulders in children with FSHD type 1, before and after balanced shoulder therapy. Secondary: To gain insight into the experience of children and parents and the…
Primary Objective: • To determine the clinical Progression Free Survival (cPFS) in our study cohort of patients with mCRPC and 68Ga-PSMA-PET/CT selected bone-only disease (PET-bone only group). The cPFS will be compared to the cPFS of patients with…
The primary aim of this study is to assess the feasibility of EM-navigation for percutaneous liver ablation.
To evaluate the feasibility, safety and potential efficacy of acupuncture in children with FC. The results of this study will be used to design a future randomized controlled trial (RCT).
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
To evaluate the acceptability and effectiveness of a deepfake victim-perpetrator confrontation in young adults with sexual violence-related PTSD.
The main objective of this study is to determine the maximum tolerated dose (MTD) of 5 fractions MRgRT for patients with AC following FLOT therapy. The secondary objectives are feasibility, non-dose limiting toxicity, oncological outcomes and to…
The primary objective of the study is to assess the feasibility and safety of sequential ETLA treatment in patients with severe emphysema with hyperinflation. The secondary objective of the study is to assess efficacy of sequential ETLA treatment in…
The objective of this clinical trial is to demonstrate that ablation with the TactiFlex* SE Ablation Catheter, Sensor Enabled* (TactiFlex PFA), in conjunction with a compatible PFA and/or RF generator, is safe and effective for the treatment of…
The primary objective of the VRAPT Arousal Pilot Study is to explore the feasibility, appropriateness and acceptability of the developed VRAPT Arousal intervention among forensic psychiatric inpatients and forensic healthcare practitioners working…
The main objective of this study is to determine the maximum tolerated dose (MTD) of 2-fraction boost MRI-guided radiotherapy (MRgRT) for patients with SCC following CROSS therapy. The secondary objectives are feasibility, non-dose limiting toxicity…
The ultimate goal is to investigate whether aVNS can enhance cortical plasticity and improve functional outcomes during intensive rehabilitation programs in children with cerebral palsy. First, we aim to establish the extent of cortical plasticity…
Our objective is to design and evaluate proof-of-concept of the WalkWell Gait reTrainer, an affordable, user-friendly continuous gait feedback system, complete with remote patient monitoring capabilities to support clinical care. We hypothesize that…
To investigate oxidative stress levels in the plasma and urine of late preterm and term newborns treated for PPHN in the NICU.
Primary Objective: To develop and validate a knowledge questionnaire as an improved version of our RAK-Q 1.0 (phase 1 and 2). Afterwards we will create a CAT (phase 3).
Primary objective: To assess whether a psychoeducational and peer-support-based intervention improves self-efficacy in individuals with neurovascular conditions. Secondary objectives: To examine the intervention’s effects on quality of life (QoL),…
Post Market Clinical Follow-up Study on the Refobacin Revision-3 Bone Cement and its instrumentation
The objectives of this study are to confirm safety, performance and clinical benefits of the Refobacin Revision-3 Bone Cement and its instrumentation, when used in hip or knee revision surgeries, by analysis of standard scoring systems, radiographs…
Main objectives:a) examine and assess the (cost-)effectiveness of WHO*s Doing What Matters in Times of Stress (DWM) in reducing psychological distress, improving mental health, and enhancing work-related well-being and productivity compared to care-…