570 results
To optimize a safe five-day intensive intravenous insulin treatment post stroke and to assess glucose profiles in patients with stroke and HG on admission, receiving standard continues enteral tube feeding.
Determine whether temozolomide given during radiation therapy followed by the combination of temozolomide and CCNU as adjuvant therapy results in an improvement in event-free survival compared to historical control cohorts.To further assess the…
To study which technique is most effective to surgically correct a symptomatic cystocele.2. To compare morbidity and post-operative recovery of anterior colporraphy and PerigeeTM.3. To compare the need for repeated pelvic floor surgery following…
To observate when necrosis in metastases of renal cell cancer is occurring.
The study objectives are1. to compare blood purification efficacy for postdilution HDF treatment in ULTRACONTROL mode to that of i) postdilution HDF using volume control mode, and ii) high-flux HD treatment, using in all treatments the same dialyzer…
Pleurodesis with autologous blood may result in shorter length of stay of inpatients who have a chest tube. This study is designed to evaluate its significance in pneumothorax patients.
The primary objective is to assess if there are any differences in terms of Bone Mineral Density between patients receiving the BICON-PLUS NT with an alumina reduced device surface (study group) and a group of patients receiving the BICON-PLUS with…
Objective of the study is to measure the effects of long term fluoxetine administration on brain- and muscle activity in combination with the effects on motor function. Main questions are:(1) Influences long-term administration of fluoxetine…
Primary objective: To evaluate the safety of Gemcitabine and Lapatinib in combination for the treatment of advanced breast cancer.Secondary objectives: Assessment of the effect of Gemcitabine and Lapatinib on the pharmacokinetics of each other and…
testing and validation of the procedures for the collection and the transport to the laboratory of the sponsor in the US (VIRxSYS, Gaithersburg, MD) of PBMC's donated via leukapheresis by HIV-1 infected persons in the Netherlands and the…
efficacy of lanreotide LAR in controling total liver volume in patients with hepatic cysts as a result of ADPKD or PCLD
STUDY OBJECTIVESTo determine whether NAC therapy results in decreased red cell PS exposure, endothelial activation, inflammation, and reduction clotting activation in the steady state.
Primary: To assess the effects of visilizumab on the safety of subsequent salvage therapies in subjects who experienced disease progression in a previous visilizumab study and subsequently received salvage therapy (see Definitions).Subjects will be…
To evaluate whether GH substitution in patients with an isolated GHD after TBI could reverse the severity of symptoms which characterize GHD.
Firstly, determination of the maximum tolerated dose (MTD) , dose limiting toxicity (DLT) and farmacokinetics in IHP with sequential administration of oxaliplatin and melphalan.Secondly, evaluation of toxicity, tumor response and survival after IHP…
This is the first study of MLN3897 in any disease population. It seeks to establish:1) The ability of MLN3897 to modify the signs and symptoms of RA.2)The safety and tolerability of MLN3897 in combination with MTX.3)The PK/PD profile of MLN3897 in…
Aim of the study is to study the influence of GH receptor polymorfisms on the effects of growth hormone substitution in aduts with GH deficiency.
Primary objective:The primary objective of this study is to assess the efficacy of lanreotide 30 mg as compared to placebo to relieve clinical symptoms due to small bowel obstruction in inoperable patients with peritoneal carcinomatosis.Secondary…
The aim of the present study is two-fold: 1) To do a survey of patients who have been prescribed a SC-KAFO in the outpatient clinic and evaluate the indication of prescription, compliance, experience and motives for (non) use of the SC-KAFO. 2) To…
The primary objective of this study is to evaluate the efficacy of SCH 503034800 mg TID PO in combination with PegIntron 1.5 *g/kg QW SC plus ribavirin (800 - 1400 mg/day) in previously untreated adult chronic hepatitis C (CHC) subjects infected…