209 results
To explore how HD mutation carriers experience suicidal ideation, plans, or previous suicide attempts (from now on jointly referred to as suicidality), how they cope with suicidality, and which ideas and wishes HD mutation carries have on how…
The main objective is to optimize the supplementation of vitamins and minerals to prevent postoperative deficiencies after MB / RYGB or GS on the long term. We also examined whether the number of outpatient visits, blood tests, and costs can be…
The objectives of the study in chronic stroke patients are 1) to determine whether eccentric strength training is an effective strength training program, 2) whether upper-limb task oriented strength training improves upper limb function in the…
The main objective of the study is to determine the PK and PD of IVIg during maintenance treatment in patients with CIDP. These data will be used to conduct a NONMEM analysis in relation to the dosage, frequency and batch of IVIg used. The secondary…
Primary objective: to quantitatively characterize the pharmacokinetics and associated inter-individual and inter-occasion variability of prophylactic nadroparin in critically ill patients.Secondary objectives: To screen and possibly quantify the…
To assess the short-term efficacy of stellate ganglion block on hot flush reduction versus sham procedure
The purpose of this research study is to compare Systane Balance Lubricant Eye Drops to Preservative-Free 0.9% Saline as necessary to support Systane Balance reimbursement in France.
The objective of this study is to assess the safety and effectiveness of the Endologix Nellix® EndoVascular Aneurysm Sealing System for the endovascular repair of infrarenal abdominal aortic aneurysms (AAA). Procedures will be performed per the…
The primary objective is to determine the effects of 12-weeks strength training on gait biomechanics and muscle strength in old adults. The second objective is to determine the relative effort necessary for level walking in young and old adults.
The primary objective of the present study is the evaluation of the vascular healing process in patients with diabetes mellitus treated with BVS implantation for NSTEMI, stable or unstable angina, or silent ischemia. The healing process will be…
To assess the effect of short term starvation and short term high fat diet on orally administered acetaminophen metabolism in healthy subjects.
We think that the results of this study could be the start of other studies and eventually lead to international standards for treatment of Achilles tendon ruptures.
The purpose of this study is to assess the safety and device success of the Edwards CENTERA Transcatheter Heart Valve (THV) System in patients with symptomatic, severe aortic stenosis who are indicated for aortic valve replacement.
Determine how many patients with IBD, treated with anti-TNF one year after change to thiopurine treatment are still effectively treated for their IBD.
To determine if Simvastatin can stimulate bone metabolism while simultaneously attenuate vascular calcification metabolism as quantified by Na18F PET CT imaging.
Identify the effect of tDCS parameters on motor learning in healthy individuals by measuring effects on visuomotor adaptation rate and retention, and study the influence of a common BDNF mutation.
The main objective of this pilot study of n-of-one trials is to determine the effect of add-on treatment with ephedrine for all participants enrolled in this small series of n-of-one trials. Secondary objectives include determining the effect in…
Primary objective:Subjective improvement of urinary incontinence (PGI-I)Secondary objectives:Objective (using stress test, padtest, bladder diaries, Sandvik score) and subjective cure of incontinence (questionnaires)Complicaties en de novo…
The main objective is to investigate whether and to what extent the QTc-time prolongs with the use of different types of antidepressants in adults treated with antidepressants for anxiety disorders. In addition we will investigate if there are…
Main objective of the study is to determine the optimal angle of illumination and intensity of blue LEDs fitted to glasses, to induce non-visual responses