90 results
To investigate the effect of nutritional prehabilitation on adverse events in patients with locoregionally advanced head and neck cancer, with low to medium risk of malnutrition and with radiological sarcopenia. To evaluate its effect on patient-…
The purpose of the VISABL-AFL study is to demonstrate safety and efficacy of RF ablation of type I atrial flutter (AFL) with the Vision-MR Ablation Catheter 2.0 in conjunction with the Osypka HAT 500 RF generator and irrigation pump. Data collected…
Why wait? (Cost)effectiveness of an online transdiagnostic therapy for patients and their loved ones
In the current study, we will analyze the (cost)effectiveness of an online, transdiagnostic positive psychology eHealth intervention for patients waiting for psychological out-patient treatment and their relatives. We expect that this intervention…
This study aims to evaluate and compare the long-term outcomes of tissue-level and bone-level single implants in the posterior region of the mandible or maxilla in patients with adequate bone for implant placement, with or without prior bone…
To elucidate whether reducing glycemic variability with hybrid closed-loop therapy inhibits the inflammatory response (e.g. leukocyte phenotype, cytokine production, inflammatory proteins) in people with T1DM. Our secondary objectives are to…
The main objective is to investigate if splintless approach improve the surgical accuracy of MMA for OSA. The secondary objectives are to assess the effect of splintless MMA on duration of surgery, blood loss, adverse events, respiration function,…
Post Market Clinical Follow-up Study on the Refobacin Revision-3 Bone Cement and its instrumentation
The objectives of this study are to confirm safety, performance and clinical benefits of the Refobacin Revision-3 Bone Cement and its instrumentation, when used in hip or knee revision surgeries, by analysis of standard scoring systems, radiographs…
Main objectives:a) examine and assess the (cost-)effectiveness of WHO*s Doing What Matters in Times of Stress (DWM) in reducing psychological distress, improving mental health, and enhancing work-related well-being and productivity compared to care-…
This study aims to assess the long-term impact of the POSE-2 procedure on weight loss, specifically focusing on the percentage of total weight loss (%TWL) over a 5-year follow-up period. Additionally, the durability and safety of the procedure will…
In this single-blinded randomized controlled trial the investigators aim to compare the OAGB and the EPGB in terms of percentage total weight loss (%TWL) 1 and 3 years postoperatively, postoperative complications and comorbidity remission in…
The primary objective is to evaluate the effect of continuing GLP-1 RA on gastric volume after standard preoperative fasting in patients using GLP-1 RA for >12 weeks. Additionally, we will evaluate the effect of withholding GLP-1 RA on…
The aim of this trial is to investigate the safety and efficacy of an adaptive anastomosis using the C-REX RectoAid Cath following elective anterior resection for sigmoid or proximal rectal cancer, or premalignant lesions not amenable tot endoscopic…
Primary Objective: The primary objective is to assess the effectiveness of HVB-assisted therapy (HV-BAT) in reducing self-reported SA.Secondary Objectives: The secondary objective is to assess the effectiveness of HVB-assisted therapy (HV-BAT) in…
Primary Objective: To study the association between muscle characteristics (contractile, morphological,biochemical, and histological) and the response to high- and low-load exercise training on muscle strength in patients with rheumatoid arthritis (…
This study aims to test if weak electric fields, as they occur during tACS, desynchronize somatosensory evoked potentials. Further, if they can, it aims to quantify at which tACS amplitude the desynchronization occurs.
To study the feasibility and safety of permissive lung–protective ventilation in adult critically ill patients receiving invasive ventilation for acute hypoxemic respiratory failure, and to inform the design of a future randomized clinical trial in…
Primary Objective:The study aims to assess freedom from AF ten years after the procedure without the use of antiarrhythmic drugs in patients who underwent thoracoscopic ablation in advanced AF with or without GP ablation. Secondary Objectives:1. To…
To evaluate the feasibility, safety and potential efficacy of acupuncture in children with FC. The results of this study will be used to design a future randomized controlled trial (RCT).
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
To evaluate the acceptability and effectiveness of a deepfake victim-perpetrator confrontation in young adults with sexual violence-related PTSD.