369 results
Objective: The primary objective of this study is to show that early detection of geriatric patients at risk of preventable functional decline following a surgical procedure under general anesthesia for a solid tumor, combined with a geriatric…
The objectives of this study are as follows:Primary Efficacy Objective:• To assess the effect of PG-760564 on the proportion of patients meeting the American College of Rheumatology 20 response criteria (ACR 20) at 12 weeks;11Secondary Efficacy…
The primary objective of this study is to assess the efficacyand safety of modifications of the laser treatment to increase the clearance of port wine stains.
To study whether in women with EP with low but plateauing serum hCG concentrations treatment with systemic methotrexate in a single dose intramuscular regimen is superior over expectant management in terms of treatment success, future pregnancy,…
1. To compare the effectivity of TVT-O and TVT-S as surgical correction of stress-incontinence. 2. To compare the complications of TVT-O and TVT-S.3. To compare the morbidity and post-operative recovery of TVT-O and TVT-S. 4. To compare the…
The primary objective for this study is to determine whether AMG 108 at a monthly dose of 250 mg SC or less in combination with MTX demonstrates a higher frequency in clinical response (ACR20) than that observed with placebo (MTX alone) in RA…
The objective of this study is to evaluate the effect of high dose MTX on skin induration in patients with eosinophilic fasciitis. In addition, we study the effect of this treatment on joint mobility, peripheral blood eosinophilia, functional…
The purpose of this project is to evaluate the combination of ER using the multi-band mucosectomy technique and RFA (HALO360/HALO90) for treatment of Barrett*s esophagus with HGD or early cancer. This will be a multi-centre European study including…
The Primary objective is to assess the long-term (6 month and 12 month) safety of the combination of aliskiren 300 mg/ valsartan 320 mg in patients with essential hypertension (msDBP > 90 mmHg and < 110 mmHg.
To compare respiratory waveforms generated using reflective markers located on the upper abdominal wall (the currently used Varian RPM system) with either magnetic sensors, belt sensors or both placed on the chest wall and/or upper abdomen. The…
To determine the clinical feasibility and performance of continuous, non-invasive FAP recording by ABM100 as a replacement of intra-arterial pressure in adult patients. Specifically, a) magnitude of pressure gradient distortion of the FAP pulse…
Primary objectives:*To evaluate the effects on labour supply (work loss days, work cut back days with lower productivity) and work productivity/functioning of psychiatric outpatient treatment (treatment as usual; TAU) vs. psychiatric outpatient…
To study the possible relation between systemic inflammation and oxidative stress and muscle breakdown using pharmacological interventions.
The objective of this study is to develop an effective behavioural treatment for severe drooling. The hypotheses are:1. A behavioural program containing instruction, goal setting, positive practice, self-management techniques, and positive and…
Primary: To prove that infliximab in combination with azathioprine is superior to azathioprine alone in rapidly inducing a meaningful renal improvement, defined as a reduction in preoteinuria of at least 50%, in patients with membranous SLE…
Identification of low allergenic apple cultivars and breeding germplasmIdentification of chains in which low allergenicity is preserved and of the critical steps in the chain for preserving low allergenicity.
To show in a prospective randomised study if intravitreal injection of Triamcinolonacetonide combined with Macula Grid Laser gives a better increase in visual acuity and/or decrease in macular edema than Macula Grid Laser combined with sub-Tenon…
Aim of the study is to describe and evaluate an alternative physical therapy management program in patients with a complex regional pain syndrome type 1. A secondary aim is to describe the adverse effects that occur during or after the intervention.
to reduce ptsd symptoms and psychological suffering in general, and to improve quality of life
The objective of this feasibility study is to demonstrate that the device is safe and potentially efficacious for use in patients undergoing high risk Percutaneous Coronary Interventions (PCI).