144 results
The primary objective of this study is to evaluate the effectiveness of lipofilling in treatment of speech and swallowing impairment after treatment for head and neck cancer. The secondary objective is to evaluate the effect of lipofilling on tongue…
To evaluate the feasibility of the study after 20 weeks of follow-up, which includes the evaluation of the dose-reduction algorithm in tocilizumab-treated patients with RA.
The purpose of this project is to investigate the presence and course of neo-antigen specific immunity in patients with polymerase epsilon (POLE) mutated endometrial cancer, with the intent to exploit the obtained knowledge of neo-antigen specific…
To evalute the efficacy of rituximab in comparison to continued corticosteroid treatment in ipatients with diopathic nephrotic syndrome unresponsive to 8 weeks of high dose prednisolone.
The purpose of this investigation is to evaluate decellularized homograft for aortic valve replacement (ARISE AV) rates in comparison to current valve substitutes within a large prospective multicentre surveillance at 6 leading European Centres for…
The main objective of this study is to develop a PDT and salvage surgery combination specific for recurrent or residual tumors of the sinonasal cavities, unsuitable for the conventional treatments like radical surgery or radiotherapy with curative…
Evaluate the effectiveness of 45- and 20-minutes post-infusion cooling time for scalp cooling in patients treated with paclitaxel in comparison with the standard post-infusion cooling time of 90-minutes
* Primary Objective: determine the functional outcome and clinical efficacy after open surgical implantation of the Ankle Spacer for patients with large, cystic, previously surgically failed and/or multiple OCDs of the talus by means of functional…
Our primary objective is to assess the differences in the incidence of short term complications (wound infection, wound breakdown and lymphocele) after IFL using LigaSure versus the conventional method. Furthermore, we will assess the differences in…
The main objective of this study is to compare the femur tunnel positioning after AMP, TLS and TT reconstruction techniques. We will also look at the relation between tunnel positioning and tunnel widening.
Bone-anchored maxillary protraction therapy improves facial profile in cleft children.
The first aim of the present study is to develop a tailor-made exercise therapy program for these complex patients. The second aim is to evaluate the effect of exercise therapy in a pilot study on cardiorespiratory fitness and several secondary…
Primary Objective is to determine if high intensity aerobic and resistance training plus psychosocial support increases overall survival compared to psychosocial support alone in patients with metastatic castrate-resistant prostate cancer.
Primary Objective: Primary aim of this study is to evaluate the effectiveness and cost-effectiveness of D(o)epression Blended in clinical practice in reducing depressive symptoms and disorders in clinically depressed adolescents. The modern and…
Primary Objective: To reduce weight after in persons with SMI in outpatient psychiatric treatment settings who are treated by Flexible Assertive Community Treatment teams (FACT-teams) after 1 year.Secondary Objective(s): To reduce cardiovascular…
This trial is intended to evaluate the safety and effectiveness of St. Jude Medical*s AMPLATZERTM AmuletTM device (Amulet) in patients with non-valvular atrial fibrillation who are at increased risk for stroke and systemic embolism. The trial will…
The aim of the present study is to conduct a randomised controlled trial (RCT) to assess the effectiveness of a guided web-based transdiagnostic intervention in treating student depression and anxiety.
Primary Objective: To evaluate the effect of PFR compared to standard treatment on FI in patients after LAR, by measuring the Wexner-score and the Fecal Incontinence Quality of Life Score (FIQL-score).Secondary objective:To analyse the cost…
Establishment of an image-guided brachytherapy procedure that is feasible for a multicenter randomized trial
The aim of this multi-centre study is to confirm the efficiency and safety of a new algorithm for calcium management after total thyroidectomy, primarily based on hypocalcemic symptoms.