129 results
Objective: Primary: Demonstrate the feasibility of PexT in patients waiting for AWR.Secondary: Demonstrate a possible effect of PexT in patient waiting for AWR on physical capacity (VO2max) and health-related quality of life (HRQL).
The SIMBA project is a research collaboration in which children with asthma, their parents and healthcare professionals play an important role. The SIMBA study is a two year program that aims to develop and finally (pilot) test an exercise game that…
Primary objectives:1) To evaluate the safety of CHMI-trans protocols in healthy malaria-naïve volunteers challenged with Plasmodium falciparum by sporozoite challenge and blood stage challenge. 2) To assess gametocyte infectiousness for Anopheles…
1. The primary objective is to assess the effects of four 250 mg PC-mAB (also referred to as "3G10") once monthly intravenous injections on monocyte function ex vivo. The secondary objectives are to:1. assess the functional effects of 3G10…
Blood glucose monitoring, cognition, and wellbeing in relation to food intake @ work * a pilot study
The primary objective of this pilot study is to investigate the relationship between glucose and cognition and wellbeing in an at-work setting. Additionally, this study aims to investigate the variability in intra- and inter individual glucose…
The primary objective of Do CHANGE is to develop a health ecosystem for integrated disease management of citizens with high bloodpressure and patients with ischemic heart disease or heart failure. The system will give them access to a set of…
1. To develop a Dutch version of the FCU, adapted to the Dutch cultural context and target group of youth with psychological and/or behavioral problems in regular and special education2. To evaluate the implementability of the FCU in the Netherlands…
Does the installation hyaluronic acid (hyalobarier ® Gel Endo), in patients with M. Asherman reduces or prevents the incidence and severity (ESGE score/classification) of spontaneous recurrence of adhesion better then the IUD without Cu or hormones…
To identify the pathophysiology and predictors of study (extreme) cancer treatment -induced cardiovascular toxicity in cancer patients, by in vitro investigation of cardiovascular toxicity in patient-derived cardiomyocytes (iPSC-CMs) and endothelial…
The aim of the present study is to implement and evaluate the 'ZELFIE game' in vulnerable geriatric patients after hip-surgery, and in patients with an increased risk of falling. The game is specifically tailored to and co-created with the…
PrimaryTo assess the preventative effect of GLPG1205 on nociceptive and inflammation/sensitization induced pain in the UVB sunburn model using HPTol upon multiple dosing of GLPG1205 versus placebo.SecondaryTo further assess the preventative effect…
The main objective of this study is to determine the most suitable diagnostic test to identify cardiopulmonary (dys)function in EC survivors treated with neo-CRT followed by surgical resection. Furthermore, we want to estimate the difference in…
The main objective of this pilot study is to: gain insight into the relationship between behavior and emotions of forensic psychiatric patients on the one hand and their physiological activity on the other hand. Unique to this research is the use of…
This study is designed to test if consumption of a vegetable extract as a food ingredient improves resistance to an experimental respiratory tract infection with RV16 in healthy volunteers.Primary Objective: * To test and quantify the effect of the…
To assess swallowing and speech function in patients ten years after CRT for head and neck cancer with preventive rehabilitation in order to compare these results with those after six years and to those of patients after CRT without preventive…
To investigate the long term (ten years) protective immune response to fractional yellow fever vaccination (1/5th of the standard dose, injected intradermally), compared to the standard subcutaneous vaccination
Primairy Objective* To test whether 5-ASA reduces the occurrence of colonic benign or malignant neoplasia compared to placebo in Lynch syndrome (LS) patients as detected by any colonoscopy until the end of study.Secondary Objectives* To test wheter…
Primary objective of this study is to assess the feasibility of using a monitoring and a titration algorithm to prevent inactivity and excessive activity of the diaphragm. This will be determined by comparing the fraction of breaths where diaphragm…
To minimize the occurrence of sub-therapeutic and supra-therapeutic C0 of tacrolimus on day 3, 7 and 10 after transplantation by basing the starting dose of tacrolimus on a dosing algorithm, rather than the standard bodyweight-only-based approach.…
To gain first insight into the association between knee proprioception and joint related neuropathic pain in patients with symptomatic knee OA.Primary Objective: To study the association between joint related neuropathic pain (measured with the…