179 results
The major objective of the present study is to examine the acute effects of dietary plant stanol esters on the intestinal mucosal gene expression profiles in intestinal biopsies in healthy volunteers. Two minor objectives are (1) to investigate…
To evaluate the effects of providing families with an activity-promoting video game on time spent playingvideo games, physical and sedentary activities, consumption of snacks and sugar-sweetened beveragesand objectively measured BMI, hip and waist…
The primary objective of this study is to investigate the effect of a meal-like amount of dietary protein prior to sleep on postprandial muscle protein synthesis in healthy young and elderly men, following exercise, during the night. Furthermore, as…
The primary objective of this study is to examine the determinants of health behavior intentions and changes in patients with TIA or ischemic stroke, and the effects of age, sex, and cognitive and functional status on these determinants as well as…
To investigate what the ideal moment to vaccinate would be, early (after 2-6 months) or late (after 9-12 months) after cessation of rituximab. Secondly to study the immune-response to vaccination with influenza virus vaccine after treatment with…
Lower tidal volumes in order to reduce VILI and days on the ventilator which will reduce the number of days on the ICU
Primary Objective: To investigate the association between the weight-loss-induced cellular stress response and the rate of weight regain. Secondary Objective: To investigate the difference in cellular stress response and weight regain after rapid…
The objectives of this study are:- to evaluate the potential of dalcetrapib to reduce cardiovascular morbidity and mortality in adult patients with stable coronary heart disease (CHD), CHD risk equivalents or at elevated risk for cardiovascular…
Primary objectiveThe primary objective of this trial is to compare TauroSept® (taurolidine 2% solution) with saline solution 0.9% as catheter lock solutions to prevent catheter-related bloodstream infections (CRBSI) in patients on home parenteral…
To quantify the impact of outpatient nurse-led prevention clinics on the risk of future clinical events in patients with symptomatic coronary artery disease.
To investigate whether Misoprostol (compared to placebo) will diminish the amount of insertion failures. To investigate whether Misoprostol (compared to placebo) will diminish the amount of insertion related complications (eg. syncope, perforation…
In The Netherlands 2% of women and 4% of men suffer from Obstructive Sleep Apnea Syndrome (OSAS). NCPAP, the gold standard therapy for moderate to severe OSAS has been shown to reduce blood pressure in OSAS. NCPAP therapy is however hampered by…
-To test the efficacy and determine the costs of a multifaceted intervention program to reduce falls incidence rate and fear of falling, and thereby improve mental wellbeing in community dwelling frail elders, with high level of comorbidity and…
For this study the aim was first to adjust the parcipatory return-to-work method for employees with nonspecific LBP to the working methods and procedures of the national organisation, responsible for counseling, disability management and activating…
The aim of this study is to get insight into bioavailability of selenium in prostate tissue and changes of gene expression profiles that might be responsible for selenium-induced chemoprevention. To meet this objective, the relationship between…
1. Primary end point is achievement of a negative cross-match test with the donor kidney and transplantability.2. Secondary objectives are patient and graft survival, graft function as assessed by calculated creatinine clearance, proteinuria, the…
To evaluate the effects and costs of indicated prevention by a multicomponent, demand led stepped care programme, compared to usual care.
The primary objective is to compare the efficacy of palifermin relative to placebo when given either pre-and post-high dose chemotherapy or pre-high dose chemotherapy only with regard to the severity of oral mucositis.
The purpose of this study is to do research what the effect of the BMI and fat percentage is on the speed of cooling.