2234 results
The questions to be answered are:1. Is vaccination with trivalent inactivated influenza vaccine in MGUS patients useful? ; Do these patients elicit adequate humoral and cellular T-cell responses after influenza vaccination?2. What is the B cell…
Primary1. To determine whether treatment with an aliskiren-based regimen (in part combined with amlodipine or hydrochlorothiazide) compared to a non-aliskiren based regimen, both on top of non-study BP lowering agents where applicable, reduces the…
The main goal of this study is to test whether offering a web-based multiple computer-tailored programme and the additional effect of a tailored counseling protocol for practice nurses to adult smokers wanting to quit within six months (preparer or…
To compare a *routine* MH strategy with an *on demand* MH strategy in cardiothoracic surgery patients with respect to post*extubation SpO2 and FRC.
PRIMARY OBJECTIVETo evaluate the time to first documented event of atrial fibrillation by 6 months continuous rhythm monitoring versus Standard of Care treatment in patients with a recent cryptogenic stroke or TIA without documented history of…
The objective of this research is to develop a method which can identify among all consanguineous couples the ones which are at high risk.
The objective is to study whether saturated fatty acids induce a different postprandial change in inflammatory markers than cis-polyunsaturated fatty acids.
The objective of this study is to compare the effects of noise with different characteristics on balance in patients with diabetic neuropathy
Primary:To determine trends in vaccine- and nonvaccine-serotype S. pneumoniae asymptomatic colonisation in healthy 11-month-old and 24-month-old infants who have been immunized according to the Dutch NIP with 7-valent pneumococcal conjugate vaccine…
In this study we want to study:1) what is the prevalence of CA-MRSA asymptomatic carriership among MSM policlinic visitors?2) What are risk factors for CA-MRSA carriership and/or infections among MSM?3) Is CA-MRSA among MSM transmitted through…
To evaluate the accuracy of trained hypo-alert dogs and to evaluate the quality of life of patients with such a dog.
The primary objective of this study is to evaluate the effect of colostrum supplementation on the immune response after intense strenuous exercise.The secondary objective is to study the effect of intense strenuous exercise - and its possible…
PRIMARY• To investigate whether calcium supplementation, in addition to standard induction therapy, decreases intestinal permeability (Chroom EDTA) in patients with active ulcerative colitis.• To observe whether calcium supplementation, in addition…
Primary: Dose finding for a twice daily regimen for PSZ as prophylactic treatment in children with CGD, based on the exposure to PSZ measured by PSZ trough levels.Secondary:To determine the tolerability of PSZ as prophylactic treatment in children…
The aim of this clinical study is to investigate whether the non-anaesthetic noble gas helium induces EPC and LPC of human endothelium in vivo.
To assess the effect of betahistine on the severity / intensity of motion sickness
To determine whether a dosing algorithm containing genetic information increases the time within therapeutic INR range during anticoagulation therapy with acenocoumarol compared to a dosing regimen that does not contain this genetic information.…
This project aims at evaluating the reliability, validity, and the practical relevance of the SDQ Self Report compared to KIVPA (a Dutch questionnaire to detect psychosocial problems in adolescents). The study findings may support the Dutch policy…
A pilot study the effect of high dose oral cholecalciferol suppletion on serum 25-OHD in elderly with osteoarthritis of the hip.
Objective of this study is the development of a national "best practice guideline on pre and postnatal follow up for prenatally detected abnormalities of the kidney and/or urinary tract". Furthermore, the guidelijne will be evaluated and…