2234 results
In this present study we will assess the effect of a pre-warming intervention before surgery, in order to decrease the temperature gradient from core to periphery and thereby minimize redistribution hypothermia under anesthesia, on (I) the…
1. To investigate the presence of risk factors for CVD (i.e. overweight/ obesity, hypertension, diabetes and dyslipidemia,) among the Ghanaian population in Amsterdam.a) To investigate levels of detection, treatment and control of hypertension among…
The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.
The objective of the study is to investigate the effects of bright light combined with physical activity during the morning on subjective and objective outcomes related to sleep-wake cycle and the rest-activity rhythm in persons with MCI, aged 65…
Primary Objective - To determine if afamelanotide can reduce the severity of PLE related pruritis.Secondary Objectives- To determine if afamelanotide can reduce the frequency of PLE episodes;- To determine if afamelanotide can reduce the duration of…
Primary Objective: The goal of this study is to assess effectiveness of a subject tailored lifestyle intervention compared with a group education program in general practice. A new perspective of changing behavior will be examined in primary care:…
• Primary objective: To achieve a 100% infection rate of human volunteers by intradermal injection of aseptic, purified, cryopreserved Pf sporozoites (PfSPZ Challenge). • Secondary objective: To compare parasite kinetics between different doses of…
The (cost) effectiveness of an intervention on energy balance related behaviours and work engagement
The study aims to develop an intervention to improve workers' energy balance related lifestyle behaviours (EBRB) to prevent overweight and to improve work engagement and subsequently evaluate the intervention developed.
The objective of the study is to estimate the prevalence of (abdominal) overweight/obesitas, metabolic syndrome (and its components), and undiagnosed diabetes in the Dutch population, aged 30-69 years. Besides, differences in lifestyle (smoking and…
The first objective is to examine the impact of 4-month walking training on physical fitness, insulin resistance and cardiovascular risks in T2DM and their controls and to assess whether these effects are preserved 3 months after cessation of the…
Our aim is to compare the effect of 8-week exercise training and exercise training under hypoxia on vascular adaptations in function and structure, but also metabolic control (insulin resistance)
The impact that the Top&Fit intervention program has on the muscle strength in subjects who are >=45 years and have an increased risk of cardiovascular diseases. The impact that the Top&Fit intervention program has on the…
To investigate whether probiotics can reduce incidence and severity of migraine attacks.
The main objective of this study is to determine if the SPC has added benefits in optimising risk factors to prevent recurrent stroke, as compared with secondary prevention performed by the GP.
Considering the high prevalence of smoking and tobacco related deaths, knowledge about the appealing function (attractiveness) of tobacco additives is highly significant, because they promote the initiation of smoking. This part of the investigation…
The objective of this study is to investigate if use of ONO-5334 has a more positive effect on bone density and biochemical markers of bone turnover than Alendronate (a bisphosphonate) and placebo.
The goal of this study is to develop and test two tailored intervention programs to stimulate pregnant women to stop drinking alcohol. These intervention programs are a health counseling and a computer tailored intervention. The efficacy of the…
To investigate the optimal timepoint of replanning during a curative radio(chemo)therapy in patients with Head and Neck cancer. Furthermore we like to analyze if the optimal timepoint of replanning is depending on tumorlocation, tumor volume or…
The objective of the study is to compare the efficacy and tolerability of mesalazine granules (3 g 5*ASA/d) vs. placebo for the prevention of recurrence of diverticulitis. Additionally, the safety and tolerability in the form of adverse events and…