2239 results
The primary objective of this study is to compare the effectiveness of two app-based interventions on diet quality and perceived stress compared to standard care.
Objective: The primary objective is to investigate the effect on vaginal mucosa damage after the application of a Medical GradeHoney formulation (L-Mesitran ®) six weeks after starting treatment in patients with pelvic organ prolapse and pessary…
The primary objective of this study is to evaluate the adherence to a 3-month gamification intervention integrated with a recently developed platform for continuous lifestyle monitoring (Care-On) in patients with recurrent atrial…
To compare the effects of three different protein-enhancement strategies (whey protein (WP), mixed plant-based protein (BRFP), and use of protein-rich food products (PFP) on exercise-induced muscle damage in older adults compared to isocaloric…
In a previous study, the validity of the FitMáx© in measuring physical condition was examined in comparison to the gold standard—an exertion test with breath gas analysis. The aim of the current follow-up study is to improve the international…
Research question:To what extent is a web-based, Cognitive Behavioral Therapy (CBT) specially designed for young gender diverse youth in the Netherlands, an effective treatment to reduce their suicidality? Are there gender, sex assigned at birth,…
To evaluate the safety and performance, including clinical benefit, of the PRIMUS System for the treatment of Resistant Migraine.
To investigate whether personalized hemodynamic management targeting baseline cardiac index reduces the incidence of a composite outcome of acute kidney injury, acute myocardial injury, non-fatal cardiac arrest, severe infectious complications, and…
The primary objectives are to examine both the (cost-)effectiveness of an innovative 1-year lifestyle intervention on lifestyle change measured by the validated Lifestyle for Brain Health Score (LIBRA) in older adults with a subjective cognitive…
The present study aims to determine whether hesperidin or a hesperidin/apigenin combined preparation can improve objective sleep duration and/or sleep quality, and/or improve perceived sleep quality and feelings of rest.
General objective:To develop or validate a clinical prediction rule for major bleeding in patients on oral anticoagulant therapy (OAT) who have been safely anticoagulated without bleeding or venous thromboembolism (VTE) recurrence for 6 months since…
We aim to evaluate the technical and logistic feasibility and safety of pre-emptive VACStent placement in patients undergoing esophagectomy with gastric conduit reconstruction, to prevent anastomotic leakage by early endoscopic vacuum therapy (EVT…
The main objective is to study to separate patients who benefit from training, from patients who do not benefit from training and identify factors that impede training capability. Secondary objective if training leads to change of aerobic fitness (…
The aim of the two separate studies is as follows: 1. To evaluate the effect of perioperative micronised lipofilling in patients with ORIF of P1 fractures on postoperative range of motion2. To evaluate the effect of perioperative micronised…
Primary Objective:The main goal of the study is to investigate the effects of a chronic increase in the gut microbial metabolite butyrate and hexanoate in the systemic circulation on peripheral insulin sensitivity in individuals with overweight/…
The primary objective is to estimate functional immune response in isolated peripheral blood mononuclear cells (PBMCs; ratio of pro-inflammatory; i.e. PGE2, IL-1β, IL-6, IL-8, IFN*, TNFα, CCL2 and CCL5, and anti-inflammatory markers; i.e., IL-4 and…
This intervention study aims to investigate the effects of daily administration of a prebiotic fiber mixture in a Nutritionally Complete Oral Nutritional Supplement (ONS) for 8-9 weeks on intestinal microbiota composition and diversity in patients…
In this project, we will conduct research within a learning and development framework to explore the barriers in adult mental health care (V-GGZ) and how and when screening and monitoring for KOPP (Children of Parents with Psychiatric Problems) can…
The overall research aim is to reduce stress in parents during PICU admission of their critically ill child by informing parents with a parent dashboard, to eventually reduce PTSD symptoms. This study seeks to reduce the negative impact of stress on…
The primary objectives are to investigate in older adults the effect of 16-week wild blueberry consumption on (regional) vascular function and insulin-sensitivity in the brain, while we will also focus on changes in cognitive performance as assessed…