138 results
Improve postoperative urine continence after prostatectomy for prostate cancer.
Primary:The primary objective is to evaluate the safety profile of an adjuvated Tb subunit vaccine (CAF01) administered in 50 µg Ag85B-Esat-6 alone, 50 µg Ag85B-Esat-6 alone with three escalating CAF01 dose levels, to four groups of healthy…
However, prior to further implementation of this programme, insight into the effectiveness is needed.Specifically, what is the effectiveness of a targeted prevention programme with regard to the prevention of DM and *in the long-term- DM-related…
Main objective is to investigate if low molecular weight fraction of edible mushroom Shiitake extract possesses clinically relevant caries preventive properties
The objective of the study is to estimate the prevalence of (abdominal) overweight/obesitas, metabolic syndrome (and its components), and undiagnosed diabetes in the Dutch population, aged 30-69 years. Besides, differences in lifestyle (smoking and…
We would like to conduct a RCT to confirm the hernia prevention effect of a mesh, however in a slightly different position, with a different mesh and with all types of stomas. In addition, we want to measure the possible benefit in terms of quality…
The effect of the dipeptide alanyl-glutamine, intravenously or enterally and perioperatively given, on postoperative insulin resistance in colon cancer patients.
For pregnant women with non-severe non-proteinuric maternal hypertension at 14-33 weeks, will *less tight* control (target dBP of 100mmHg) vs. *tight* control (target dBP of 85mmHg) increase or decrease the likelihood of pregnancy loss or neonatal…
Primary objective:To determine the relationship of route of gastroenteric anastomosis after PD and postoperative incidence of DGE.Secondary objectives:To determine the relationship of route of gastroenteric anastomosis after PD and gastric emptying…
1) To evaluate the efficacy of knee-ankle-foot orthoses (worn by night) in preventing a decrease of range of motion to ankle dorsiflexion in children with cerebral palsy (Clinical part). 2) To evaluate the effect of night-worn knee-ankle-foot…
Patients in whom a permanent (end) colostomy is created in (semi) elective setting are randomised between the placement of a polypropylene mesh during stoma creation and the classic method without a mesh. Primary aim: Does the use of a lightweight…
Goals of the proposed study are to empircally test the course 'The stories we live by" on:1. The effectiveness in reduction of depressieve and axiety symptoms;2. The effectiveness in improvement of quality of life and psychological health;…
The objective of this study is to compare the effects of noise with different characteristics on balance in patients with diabetic neuropathy
In this study we want to study:1) what is the prevalence of CA-MRSA asymptomatic carriership among MSM policlinic visitors?2) What are risk factors for CA-MRSA carriership and/or infections among MSM?3) Is CA-MRSA among MSM transmitted through…
PRIMARY• To investigate whether calcium supplementation, in addition to standard induction therapy, decreases intestinal permeability (Chroom EDTA) in patients with active ulcerative colitis.• To observe whether calcium supplementation, in addition…
To study the immune response to vaccination with influenza virus vaccine, conjugated Hib and pneumococcal vaccine after treatment with rituximab in association with the reconstitution of immune function (in terms of amount of B-cells and…
To assess whether supplemention of vitamin D3 (1200 IU/day) in vitamin-D deficient non-western immigrants at risk for type 2 diabetes mellitus can improve the insulin resistance and betacell function as well.
Objectives:1: Increasing the awareness of the older adults of the importance of physical activities2: Introducing the elderly to physical activities and familiarizing them with the fun of it3: Increasing physical activity, improving or maintaining…
The objective of this study is to assess fatigue, physical activity, psychological wellbeing and quality of life in breast cancer patients during and shortly after adjuvant chemotherapy. We will study how often en how intense the symptoms occur. We…
Objective of the study is to make this CODIP module applicable for the Dutch situation and to test it in anextensive pilot study to such extent that a decision about national implementation can be made.Therewith the feasibility study has three goals…