65 results
The aim of the study is to establish depression and suicide prevention reaching students who attend special education.The primary goal is to evaluate the effectiveness on depressive symptoms of a screening and prevention program for adolescents who…
Objective: To demonstrate that smoking cessation in the postoperative period has a positive impact on the clinical and radiological outcomes of instrumented spine surgery
This study has been transitioned to CTIS with ID 2024-518686-10-00 check the CTIS register for the current data. To describe and investigate safety and tolerability of the intradermal delivery of two fractional doses of 3/3 µg Comirnaty Original/…
Our primary objective of the feasibility study is to assess the acceptability and feasibility of the developed 2EAT dietary treatment in older adults with obesity. The primary objective the main study (RCT) is to investigate whether a shift towards…
In the current study, the feasibility, acceptability and effectivity of a new add-on early intervention program for individuals at risk for the development of bipolar disorder is evaluated. This intervention program entails psycho-education, light…
The current study aims to investigate two types of sleep interventions in night shift workers: a split sleep intervention strategy and a short sleep episode (powernap, max. 20 min) during a night shift. It will assess the effects of the two…
To determine the effect of a five-week vegetarian diet on innate immunity of patients with a recent myocardial infarction and healthy participants.
To study the possible epigenetic modifications in sperm cells after BCG vaccination
The primary objective of this study is to demonstrate the effect of consuming daily 5 grams of Agaricus bisporus powder (10 capsules) on the vaccination response to an influenza vaccine in men and women aged 60 years or older during the influenza…
To investigate the effect of low-dose rhythmic transdermal 17-β-estradiol on serum P1NP (marker of bone formation) and CTX (marker for bone resorption), versus continuous low-dose and standard-dose continuous transdermal 17-β-estradiol…
The main objective of the 2DIAREM study is to develop minimally invasive alternatives of diabetyping. Two alternative sampling methods will be evaluated, capillary sampling and continuous glucose monitoring (CGM). Data collected through these…
The primary objective of this study is to assess the individual patients* response to an exercise program on aerobic capacity at six weeks by measuring the VO2 at the VAT and VO2peak before and after a homebased bimodal lifestyle program in non-fit…
The primary objective of the proposed study is to isolate and characterize neutralizing Lassa-specific monoclonal antibodies from LASV recovered individuals.
To describe and investigate safety and tolerability of the intradermal delivery of two fractional doses of 20 µg mRNA-1273 in patients with Fibrodysplasia Ossificans Progressiva.To compare the immunogenicity of patients with FOP after intradermal…
Primary objectives: To evaluate the efficacy of long-term prophylactic treatment with deucrictibant (PHA-022121) in preventing breakthrough angioedema attacks in patients with AAE-C1-INH. Secondary objectives: To evaluate the safety of long-term…
This study is aimed at understanding status and future cardiovascular disease (CVD) risk in UC outpatients in remission undergoing different anti-inflammatory therapeutic regimens (tofacitinib (a JAK1 - inhibitor), anti-TNF (infliximab or adalimumab…
Primary: To assess the effects of a 12-week self-composed vegan diet in comparison to an omnivorous diet on thigh muscle volume (TMV) in community-dwelling older adults. And to assess the effect of a 12-week self-composed vegan diet combined with…
Primary Objective: Investigate the difference in composite endpoint MACE, major amputation, or target vessel revascularization in PAD Fontaine II patients with and without antiplatelet resistance as measured by a. VerifyNow b. Genetic testing of…
This project therefore adopts an urgently needed comprehensive individualized approach. We characterize each participant in a large sample of individuals varying in bodyweight by their own baseline comprehensive profile, including person…
The main objective is to investigate whether preoperative TRF improves perioperative insulin resistance compared to CHL and standard preoperative fasting.Our secondary objective is to investigate the feasibility of preoperative TRF in terms of…