130 results
Mortality will be lower in patients who do not smoke during treatment of non-small cell lung carcinoma with PD-L1-inhibitors compared to patients who smoke during their treatment with PD-L1-inhibitors.
To contribute to building a sound scientific basis for the regulatory EU institution to set-up occupational exposure limits and related biological limit values, as well as reference values for the general population and to study the impact of the…
The aim of this study is to investigate the extent to which changes are observed in a physically active man, aged around 85 years in 1) PIFMs* size, 2) dynamic balance and 3) foot function during gait after participating in a PIFM strengthening…
The main objective of this study is to validate the accuracy of the device to monitor the physical activity of a subject by comparing the measured values to the golden standard (video recording).
The primary aim of this study is to examine the feasibility, usability, and acceptability of the educational care pathway for both patients and healthcare professionals. The secondary aim is to investigate the preliminary effects on patients*…
Phase 1 • Primary objective: to determine the safety and tolerability, including the attenuation phenotype of a novel late-arresting GAP, named GA2 parasite, administered by sequentially increasing numbers of mosquito bites.• Secondary objective: to…
The primary objective is to determine the bifidogenic effects of a 4-week intervention with one of four dietary supplements (Chondroitin sulfate, NOVELOSE® 3490, and Pea Fiber, and Lactium®) in IBS patients. The secondary objective is to determine…
We have defined the following milestones/deliverables for this project:1. Evaluation of IgG antibody response in pregnant women after participation in the Dutch national COVID-19 vaccination program.2. Evaluation of the relation between gestational…
To investigate whether treating children with high refractive errors at age one with glasses prevents the development of amblyopia.
To compare the in vitro potency of commonly used antiplatelet drugs in the blood of patients with various stages of fibrosis due to MAFLD, compared to that in blood of individuals without underlying liver disease.
To determine the impact of prior BCG vaccination on the duration of immunogenicity of the BioNTech/Pfizer mRNA COVID*19 vaccine.
This study has been transitioned to CTIS with ID 2024-517846-32-00 check the CTIS register for the current data. To evaluate the effect of prolonged duration of (fos)aprepitant prophylaxis on the prevention of delayed CINV (complete remission in the…
Primary Objective: To evaluate potential changes in body composition and REE after NMES therapy at home for 12 weeks.We hypothesize that NMES therapy would result in hypertrophy of gluteal and hamstring muscles, and an increase in LL-LBM, total LBM…
Clinical Trial Protocol section 2.The main objectives of the trial are to assess the safety and tolerability of two doses of ABNCoV2, formulated with and without the adjuvant MF59, in healthy adult volunteers and to identify the dosage and…
Investigate whether continuous monitoring of physical activity with an activity tracker leads to an improvement in preoperative endurance in elderly people with colorectal cancer, compared to a standard preoperative route with prehabilitation.
Objective: Evaluation of safety and initial efficacy of a novel fusion-protein based anti-COVID19 vaccine in healthy volunteers.
The aim of this research is to find out whether eating Broccocress®, a sprout vegetable rich in the substance sulforaphane, can counteract inflammation caused by, among other things, unhealthy food. More precisely, we are investigating whether…
The primary objective of this study is to demonstrate clinical benefits of consumption of plant stanols (delivered via products enriched with plant stanol esters) on the vaccination response to a COVID-19 vaccine in overweight or obese patients aged…
To asses if there is a difference in functional outcome between open reduction and fixation of the posterior fragment in trimalleolar AO-Weber B fractures with additional medium-sized posterior fragment (5-25% of the involved articular surface, AO…
To investigate the impact of different types of proteins on muscle damage upon an endurance exercise bout in elderly.