141 results
The primary objective of this study is to evaluate if there are differences in the tissue-interface pressures, pressures inside the tissues and tissue deformation in the sacral area when volunteers lie on a regular spineboard versus a vacuum…
Primary: to demonstrate the superiority of at least one dose of canakinumab compared to placebo in reducing the risk of recurrent major cardiovascular disease events (cardiovascular death, non-fatal MI and stroke) in a population of clinically…
To compare the effect on the corneal endothelium of ICSAC during vitrectomy.
Primary Objective: The primary objective of our study was to prospectively study the fecal acquisition of NDM-1 carbapenemases producing Enterobacteriaceae during foreign travel and the persistence rate of acquired NDM-1 carbapenemases producing…
Primary: • Assess effect of AN-PEP on gluten epitope degradation in the duodenumSecondary: • Assess effect of AN-PEP on gluten epitope degradation in the stomach• Assess effect of meal caloric content on the efficacy of AN-PEP on gluten epitope…
To prove that lymph vessels in the legs can be visualized with methylene blue, so they can be spared during surgery, what possibly may lead to decreased postoperative lymph edema.Hypothesis: Methylene blue visualizes lymph vessels in the legs, so…
Time to recurrence of sustained VT and/or appropriate ICD therapy; ATP or shock
Objective: Determination of cross-reactivity to a newly developed PPD-derivative (F000175918) in previously PPD-sensitized patients. Hypothesis:Since PPD-derivative F000175918 is categorized as a moderate sensitizer, based on pre-clinical…
PrimaryTo assess the efficacy of scalp cooling in preventing allopecia due to Myocet chemotherapy by the objective method of trichometry. Secondary:* Assess the efficacy of scalp cooling by comparing the objective method (trichometry) with the…
Study the effect of a plastic cap during the resuscitation of a preterm infant on heat loss and temperature at admission to the NICU.
The aim of the study is to evaluate the efficacy of Ardox-X® Technology on the inhibition of de novo plaque formation and changes in the microbial composition in periodontally healthy patients in a one-week non-brushing model.
The primary objective is to determine the effect of (1) increased sodium intake and (2) increased potassium intake on flow-mediated dilation (FMD) and systolic blood pressure (SBP) in untreated (pre)hypertensive subjects
Primary objective:Determine the incidence rate of inhibitor formation in PUPs with severe and moderately severe hemophilia A during the first 50 exposure days (EDs) to starting with a once weekly prophylactic regimen together with the minimization…
exclusion or demonstration of a diverticulum in patients undergoing a laparoscopic pull-through
1) To investigate the impact of keeping/loosing diabetes on quality of life and psychological well-being in a group of (morbidly) obese patients who underwent bariatric surgery, and 2) To explore whether we can predict postoperative quality of life…
The main objective is to translate and adapt the Adolescent Cannabis Check-Up (ACCU) to the Dutch context and setting, and to evaluate its effects on the cannabis use of adolescents in the Netherlands. The Dutch version of the ACCU is called Wiet-…
Primary objective:To determine whether moderate alcohol consumption with a meal in different ambiances affects postprandial mood, evaluated by subjective (POMS, B-BAES, PPW questionnaires) and physiological (ACTH, cortisol, TRP:LNAA ratio, ghrelin…
The objective of the study is to investigate effects of training on insulin resistance (IR), chronic heart failure (CHF) and cognition of resthome residents.
The main objective of this study is to determine if the SPC has added benefits in optimising risk factors to prevent recurrent stroke, as compared with secondary prevention performed by the GP.