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Risk factors for Intensive Care admission of children with severe acute wheeze or asthma

Primary Objective: To prospectively assess the impact and relevance of several risk factors for SAA/acute wheeze that have been identified in retrospective studies, including our own. Secondary Objective: To assess short-term medical and…

Strong teens and resilient minds: School-based prevention of depression and suicide

The primary goal is to evaluate the effectiveness of a screening and prevention program for adolescents who experience depressive symptoms. The secondary goal is to find factors which possibly relate to the effectiveness of the prevention program.…

Infection prevention and immune modulation by bacterial lysates in patients with asthma: gaining insight into the mechanism of an old therapy

To diminish the number of asthma exacerbations with the regular use of a bacterial lysate.

Five year follow up of duplex investigations in young patients with a history of suspect venous disorders

Follow up of 38 patients who had a duplex investigation in the past when they were 18 years old or younger.

Virtual reality exposure before elective pediatric day-care surgery: effects on pre- and postoperative anxiety and pain

The objective is:(1) To test the efficacy of VRE versus CAU in 200 children undergoing surgery on the anxiety level of the child during induction of anesthesia (primary outcome), pre- and postoperative child anxiety, pre- and postoperative parental…

Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY): A Multi-Center Randomized Controlled Study Comparing Alternative Antibiotic Regimens in Patients Undergoing Tumor Resections with Endoprosthetic Replacements

The objective of this study is to determine whether long term (5 days) postoperative (cefazolin) antibiotics will decrease the rate of infection following lower extremity tumor surgery, when compared to short term (24 hours) postoperative (cefazolin…

A comparison of Glycosade® and Uncooked Cornstarch (UCCS) for the dietary management of hepatic glycogen storage diseases (GSD)

In light of the variability in response between UCCS and Glycosade® in patients with hepatic GSD (personal communication from authors and published data (Bhattacharya et al. 2007; Correia et al. 2008; Corrado M et al, 2013; Hubert A et al, 2013));…

Influence of the dietary history on the prevention of celiac disease: continuation of the PreventCD study (PreventCD2).

Primary: to evaluate the effect of the intervention of PreventCD at age 18 years in terms of frequency of CD and CD autoimmunity.

The predictive value of the acute effect of beclomethasone-dipropionate on an exercise-challenge test for the outcome of longterm treatment with beclomethasone-dipropionate in childhood asthma.

This study aims to investigate if there is a correlation between the severity of bronchoconstriction after an exercise challenge test 6h after a single dose of Qvar and after 4 weeks of treatment with Qvar, in order to know if the respons to a…

Effectiveness of an online cognitive behavioral group intervention for adolescents with a chronic disease and parents: A randomized multicenter controlled trial

The main objective of the study is to research the effectiveness of two online cognitive behavioural therapeutic courses; a course for adolescents with a chronic illness and a course for parents of children and adolescents with a chronic illness.…

Placebo-controlled trial in subjects at ultra-high risk for psychosis with omega-3 fatty acids in Europe

Primary objective of this randomised controlled trial is to compare transition rates to psychosis between individuals who are at UHR for developing psychosis and randomised to treatment with omega-3 fatty acids to those randomised to placebo, as…