17 results
To identify the pathophysiology and predictors of study (extreme) cancer treatment -induced cardiovascular toxicity in cancer patients, by in vitro investigation of cardiovascular toxicity in patient-derived cardiomyocytes (iPSC-CMs) and endothelial…
The aim of this study is to investigate the effect of ARTISS compared with our standard care on total volume of donor site seroma after harvesting a LD in immediate breast reconstruction. Seroma is diagnosed, when >= 20 mL can be punctuated…
to determine whether a pre- and postoperative CR (PRE+POST) program improves the short (up to three months) and long term outcomes (up to one year) after cardiac surgery (i.e. reduction in postoperative surgical complications, readmissions to…
The primary goals of this project are to 1) evaluate the effectiveness, 2) identify effective elements and 3) find successful implementation factors of an integrated group-based lifestyle intervention programme in primary care.
To investigate the occurrence of live birth in women with TS after ovarian tissue cryopreservation in childhood followed by auto transplantation in adulthood.
In the current protocol we describe 2 work packages in which we aim to perform: A. >=2 focus-groups to gauge acceptability of the smartphone-app (WP1); B. follow-up remitted patients with recurrent MDD for 1.5 year while the background app (…
The global aim of this project is to determine the immunophenotype-genotype interactions of PC. The novel insights in the molecular genomic and immunological profile of the tumor tissue and metastases are expected to help determine the immune…
Our research aim is fourfold:1) We aim to assess the effect of hypertension on functional and structural markers of the brain using 3 tesla (T) and 7T MRI in patients who are temporary drug naïve and will be switched-on to medication as part of…
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This study aims to explore perceptions of care and needs of support in a suicidal crisis family members and suicidal patients (in current remission). Mapping these experiences will contribute to an emerging theory to guide care for suicidal patients…
The purpose of this study (APPIRED III) is to investigate the efficacy of administered prophylactically RESCAP with regard to the prevention of (severe) renal failure, or renal dysfunction, reducing morbidity and mortality. It also looks at systemic…
Primary Objective:The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in…
This study has been transitioned to CTIS with ID 2024-519386-21-00 check the CTIS register for the current data. The central aim of the POEM Study: to investigate whether the early start of metformin on top of standard care may improve the treatment…
To study the renoprotective effect of potassium supplementation in patients with CKD (stage 3b or 4 or estimated glomerular filtration rate [eGFR] 15 - 44 ml/min/1.73 m2).
Primary Objective: Primary objective of this trial will be to determine whether iNPWT reduces the number of patients with clinically relevant* SSOs after (potentially) contaminated ventral hernia repair <30 days after surgery. *A SSO is…
Primary Objective: To assess the efficacy and safety of faecal microbiota transfusion in female renal transplant recipients with intestinal carriage of extended-spectrum β-lactamase Enterobacteriaceae (ESBL-E) and/or carbapenemase producing…
To develop and test an innovative evidence-based therapeutic tool (EMDT add-on intervention) that reduces the frequency and intensity of intrusive suicidal images and thoughts, in order to prevent the transition from suicidal ideation to suicidal…