12 results
1.3. Study Design Rationale The ATLAS-INH trial (ALN-AT3SC-003) is a multicenter, multinational, randomized, openlabel Phase 3 study designed to demonstrate the efficacy and safety of fitusiran in patients with haemophilia A or B with inhibitory…
This study concerns a pilot implementation and evaluation of FAME. - It aims to provide an initial indication of the efficacy of FAME in families in two living conditions: asylum centers and family locations. It is hypothesized that FAME has a…
To examine the effect of a physical activity intervention on executive functioning, mental health and academic achievement in healthy adolescents. The secundaire objective is to examine the effect of a physical activity intervention on physical…
The primary objective is to evaluate the effect of the PAL-system on diabetes self-management determinants and behaviour and as a result on the health of children with T1DM. The PAL-System consist of a robot and a MyPAL-app, containing an avatar of…
The primary objective of this study is to investigate the neuro-endocrine development of socio-emotional control related to automatic emotional action tendencies, the structural maturation of the brain, and how these contribute to cognitive control…
The purpose of the overall project is to adapt an existing self management tool for adults to the needs of young people and how to implement the adapted app within the youth mental health. The overall project consists of three different phases with…
The primary objective of this project is to map differences in joint loading between athletes receiving visual feedback and those who will not receive visual feedback in both retention and transfer to field-specific situations. From there. we will…
1.3. Study Design Rationale The ATLAS-PPX trial (ALN-AT3SC-009) is a multicenter, multinational, open-label Phase 3 switching study designed to demonstrate the efficacy and safety of fitusiran in patients with hemophilia A or B, with inhibitory…
Primary objectives:1. To quantify physical activity, sports participation and exposure according to age, haemophilia severity and joint status;2. To assess the incidence of sports-related injuries in those who participate in sports at least once…
The objective of this open-label extension (OLE) study is to assess the effect of long-term safety and treatment effect of Voxelotor in participants who have completed treatment in Study GBT440-031, using the following parameters:- Safety based upon…
The current project aims to address the three barriers that obstruct children from profiting optimally from CBT. For this purpose, an easy accessible, online, CBT-based training for anxious children (aged 8-13 years) will be developed and assessed…
Primary research questions:(1) What is the rate of persistent DSM-5 moderate to severe SUD from adolescence to young adulthood among youth in addiction treatment?(2) What is the prognostic value of a general population-based set of predictors of…