312 results
The overall research aim is to reduce stress in parents during PICU admission of their critically ill child by informing parents with a parent dashboard, to eventually reduce PTSD symptoms. This study seeks to reduce the negative impact of stress on…
This intervention study aims to investigate the effects of daily administration of a prebiotic fiber mixture in a Nutritionally Complete Oral Nutritional Supplement (ONS) for 8-9 weeks on intestinal microbiota composition and diversity in patients…
To study the efficacy of preoperative CBM in patients with increased anxiety levels undergoing knee- or spine surgery with expected postoperative moderate to severe pain.
To investigate the impact of different doses of handgrip exercises (moderate vs high intensity) and stimuli (exercise vs ischemia) on the ability to protect endothelial damage from ischemia-reperfusion injury in healthy humans. A secondary goal is…
The aim of this study is to investigate the effects of breastfeeding on lipid profile and cardiovascular risk markers in women with familial hypercholesterolemia (FH). In addition, breast milk composition and the transfer of statins to breast milk…
This study aims to investigate the effectiveness of a multicomponent intervention in promoting physical activity among adults with ID.
The aim of this research project is to assess the feasibility and acceptability of an adapted version of Group Interpersonal Therapy [IPT] for parents from refugee backgrounds in primary care in The Netherlands. Moreover, the potential effectiveness…
The primary objectives are to investigate in older adults the effect of 16-week wild blueberry consumption on (regional) vascular function and insulin-sensitivity in the brain, while we will also focus on changes in cognitive performance as assessed…
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Primary objective:To evaluate patient survival after direct procurement and hypothermic oxygenated machine perfusion of DCD donor hearts using the XVIVO Heart Assist Transport System.Secondary objective(s):The secondary objectives are to evaluate…
To validate a rhinovirus controlled human infection model, investigating the time course of infectious and immunological parameters after inoculation with an RV16 inoculum and to compare the response of volunteers without (part A) and with (part B)…
This study aims to investigate (1) the effectiveness of Nordic Hamstring Exercise for preventing hamstring re-injuries (2) the effectiveness of Nordic Hamstring Exercise for enhancing performance following Return to Play after hamstring injury.
For this study, we will: - Quantify health literacy and numeracy in people with type 1 or type 2 diabetes on intensive insulin therapy (Multiple daily injections of insulin (MDI), or continuous subcutaneous insulin infusion (CSII)) - Examine the…
The primary objective of the current pilot study will be to assess the feasibility of participant selection methods to identify individuals with cam morphology free of hip OA.Secondary objectives includea) the evaluation of the willingness of…
Primary Objective: Assess the leakage of FFP2 respirators and surgical masks in human subjects using inhalable aerosols consisting of a solution of fluorescein in water.Secondary Objective(s): (a) Study the variability in total inward leakage of…
The purpose of this study is to determine the feasibility of sports-specific CTR in athletes.
To compare the effect of a 6-month of enriched care consisting of additional protein intake and regular resistance exercise on the prevalence of disproportional fat-free mass loss (defined as a FFML/WL >30% as main outcome parameter) in…
Usability of oat-coated gloves (intervention) and the effect on skin condition in comparison to non-coated gloves (care as usual).
Primary objective:- Determine the number of unruptured IAs in smoking women aged 50-60 years in the Dutch population in a cohort of 55 participants. Secondary objectives:- Evaluate the possible changes in quality of life associated with a screening…
The purpose of the pivotal study is to determine the safety and efficacy of IMPEDE-FX RapidFill for increasing the percentage of subjects with shrinkage of the abdominal aortic aneurysm sac when used as an adjunct to on-label EVAR stent graft…