312 results
The primary objective of this study is to assess the individual patients* response to an exercise program on aerobic capacity at six weeks by measuring the VO2 at the VAT and VO2peak before and after a homebased bimodal lifestyle program in non-fit…
To determine the feasibility of at-home monitoring patients with oesophageal cancer during chemoradiotherapy.
The primary aim of the study is to evaluate whether treatment with the EKOS device on top of anticoagulation in patients with severe pulmonary embolism results in a better clinical outcome than treatment with anticoagulation alone. The primary…
To assess risk factors for cardiomyopathy and heart failure among lymphoma (HL and aggressive B-cell NHL) survivors, focusing on the independent and joint effects of doses of anthracycline-containing chemotherapy (doxorubicin) and rituximab as well…
To study the potential of the daily use of a mini-trampoline or metformin added to the NHG -guided lifestyle to cure early type 2 diabetes in overweight and obese patients. PICO research question. What is the effect of the mini-trampoline or…
The aim of this study is to lower suicide rates in Noord-Brabant with 20% by establishing a chain of care and a suicide prevention system in this regional network of chain partners. To this end, two sub-objectives are: (1) to evaluate the effect of…
The first aim is to test the effectiveness of the school-based targeted prevention program for youth with mild intellectual disabilities and behavior problems (e.g., aggressive and oppositional defiant behavior) at reducing behaviour problems. The…
The effectiveness of an e-health intervention will be tested by means of a randomized controlled trial. The control condition consists of psycho-education on pregnancy, stress and smoking. The primary outcome measure is smoking (frequency of women…
The primary aim of the study is to improve the oral cleanliness of young high caries active children by a HAPA-based intervention to improve the brushing behaviour of parents in their children. Therefore, the effect of the HAPA-based intervention is…
The present project consists of 2 studies (study 1 & study 2) and is an extension of a recently conducted study in healthy young adults. The overarching goals of the project are to provide insight into (i) the development of cautious gait…
The primary objective is to determine the effect of ICU-VR at three months after discharge on psychological sequelae and HRQoL up to 6 months after discharge in patients treated for COVID-19 on the ICU. The secondary objective is to determine the…
Relapse after an intensive rehabilitation program is a problem, the additional intervention which is developed aimed to prevent this. The intervention is innovative and no alternatives are known in the literature.The following practical questions…
The primary objective of this study is to assess the effectiveness and cost-effectiveness in terms of the number of surgeries prevented of a combination therapy versus usual care.The secondary objective of this study is to assess the effectiveness…
The aim of the current study is to determine whether a *liberal* strategy of maintaining Hb concentrations above 9 g/dL would result in a different neurological outcome when compared to a *restrictive* approach to red-cell transfusion to avoid…
Main objective of the trial is to determine the effect of individualizing the immunosuppressive therapy based on baseline immune-risk stratification according to 2 new biomarkers (d-sp ELISPOT IFN-γ and donor/recipient HLA Eplet Mismatch), in a…
To investigate the effect of a dietary intervention based on a WFPD on serum uric acid levels, gout disease activity and cardiovascular risk in patients with gout.
Primary Objective: to compare the effects of two interventions on lifestyle behaviour (food intake and physical activity) and quality of life in people with T2DM. The interventions include the National Diabetes Challenge (*NDC-only group*), and a…
Objective: To test if participants with autism engaging in a CBT-I based online guided intervention (i-Sleep Autism) will experience a significant reduction in insomnia symptoms and improved mental health outcomes compared to the control group (…
Primary intervention objective: to evaluate change in emotion dysregulation in at-risk-for-ADHD toddlers (24-36 months) during the 8-week intervention period of MASTER compared to the 6-week baseline (control) period. Secondary intervention…
Our aim is to identify cognitive dysfunction in patients with a cerebellar pontine angle tumour (koos classification grade 4 schwannoma) that have been operated in order to prevent cognitive decline in future patients. For this purpose, we want to…