193 results
The primairy objective of this study is to investigate whether beta cell mass is correlated to beta cell function after autologous faecal microbial transplantation (FMT) in patients with newly diagnosed type 1 diabetes after FMT. Within 1 month…
Primary objectives -To determine whether real-time tumor visualization using targeted fluorescent imaging during breast conserving therapy in breast cancer patients can be achieved intraoperatively and results in adequate assessment of the tumor…
PRIMARY OBJECTIVETo assess the diagnostic performances (specificity, sensitivity, positive and negative predictive values) of monitoring blood biomarkers (T-Ag antibodies and miR375 levels) for detection of recurrence of disease during follow up.…
To assess the presence of small vessel disease (i.e. WMHs, lacunes, microbleeds, perivascular spaces, and recent small subcortical infarcts) based on 3 tesla brain and carotid MRI in patients with ECAA.
To develop an innovative magnetic resonance imaging (MRI) protocol(M-ILD) for accurate phenotyping and sensitive monitoring of therapy in ILD patients.
Primary Objective: The primary outcome of this study is successful implementation of home-based blood sampling. The success criteria is that 25% or more of the blood assessments are actually performed at home by the patients themselves using a self-…
The goal of this study is to asses wheter testosterone contamination is caused by appliction of testosterone gel on the phlebotomy site or on the forearm.If previously mentioned study is supported by the current study, the testosterone/estradiol…
The primary objectives of this study are to: (i) derive quantitative measures of behaviour on the basis of smartphone monitoring in a healthy cohort and a cross-diagnostic cohort of patients with mental disorders (e.g. depression, anxiety and…
Primary objective: We aim to examine whether the Cobb angle measurements are similar on a full spine x-ray compared to a targeted x-ray, following traumatic spinal injury in patients >55 years of age, after 3 and 12 months of follow-up.
We aim to study the rate of developing a biopsy-based diagnosis of high-grade dysplasia (HGD) and EAC in BE patients in a prospective cohort of 204 BE patients at high risk of progression (i.e. after endoscopic removal of visible lesions containing…
Although this procedure has been performed for more than 20 years and clinical results after myectomy combined with AMVLE are satisfactory, very little is known about the effect of surgical myectomy intervention on the blood flow through the aortic…
- to explore the decline in renal concentration ability (RCA) in a Dutch population of lithium treated patient - to explore the decline in kidney function
Primary Objective: 1. To investigate the effect of CRT on markers of pancreatic exocrine functioningSecondary Objectives: 1. To compare changes in markers of pancreatic exocrine function between CRT responders and non-responders2. To compare the…
Primary objective: - obtain an comparison in diagnostic results of two methods of ultrasound assisted fine needle aspiration biopsies (FNAB) of the thyroidal gland in the Jeroen Bosch hospital (JBZ).Secondary objective:- can the cytological thyroid…
The primary objective of this study is to determine the accuracy of the delta PCO2 (PaCO2-tcPCO2) and delta PO2 (tcPO2 -cPO2) levels for the detection of sepsis. The secondary aims are to determine the factors that influence delta PCO2 and delta PO2…
This study has been transitioned to CTIS with ID 2024-517718-13-00 check the CTIS register for the current data. Primary Objectives:To determine the optimal dose of the VEGF-targeting optical agent Bevacizumab-IRDye800CW for an adequate tumor-…
To determine the safety and feasibility of fluorescence imaging of the eye vascularization with the fluorescent tracer bevacizumab-800CW for identification of neovascular Age-related Macular Degeneration (AMD) with scanning laser angiography.
To determine the technical feasibility of cholangioscopy using the Spyglass DS II system in the pre-operative work-up of resectable EC.
Primary Objective: To investigate the yield of two methods of exhaled breath analysis (PCR based and VOC based) in the detection of Pseudomonas aeruginosa colonization or infection in young patients with cystic fibrosis (CF).Secondary Objective(s):…
This study aims to validate the efficacy of a wireless and small EMG sensor as a tool for monitoring asthmatic children. We will analyse differences in diaphragmatic muscle activity as measured with this EMG sensor before and after administration of…