217 results
1. To identify and specify bacteria by using RT-PCR on blood and cerebrospinal fluid (CSF) in preterm infants, having nosocomial sepsis and meningitis.2. To compare RT-PCR (see aim 1) with the gold standard bacterial culture in preterm infants,…
Primary objective:1. To investigate the clinical value of [18F]Flutemetamol PET in memory clinic patients and especially those with suspicion of young onset dementia in terms ofa. change in (level of confidence of) diagnosis;b. impact on patient…
Primary Objective• To validate the existing demarcation formula (consisting of psychometric and biological markers) which predicts the sensitivity to Lybrido or Lybridos in women with female sexual interest/arousal disorder (FSIAD with or without…
Assessment of the diagnostic accuracy of CTA for the detection of vasospasm after SAH in comparison to TCD.
The aim of the study is to investigate the differences in multi-joint coordination between healthy young and healthy elderly. Secondly, we want to study adaptation of ankle and hip strategy with the application of whole-body force fields and…
4.1 Primary• To estimate the Sensitivity and False Positive rate of OTL38 for malignancy detection during Near Infrared Imaging (NIR).• To assess the safety and tolerability of single intravenous doses of OTL384.2 Secondary• To assess the safety of…
The primary objective is to investigate the quality (whether assessable by a pathologist or not) of the endometrial sample obtained by aspiration when performed directly before or after the SIS in postmenopausal women. Secondary objectives are to…
1. Determine body composition of MD patients;2. Determine physical function of MD patients;3. Determine the association of body composition and physical function of MD patients.
To monitor and describe the natural motor learning of handrim wheelchair propulsion during usual care in a Dutch spinal cord injury rehabilitation center. Motor learning is operationalized as change in mechanical efficiency, propulsion technique and…
The main objective is to examine if 68Ga-exendin tracer accumulation (i.e. beta cell mass) differs in patients with persisting HH after RYGB compared to matched patients without HH after RYGB. The secondary objectives are:- compare GLP1 and GIP…
The UPGRADE-RT trial will investigate whether de-escalation of the elective radiation dose and introduction of an intermediate dose-level in the treatment of head and neck cancer will results in less radiation sequelae and improved quality of life…
Primary:To understand the relationship between novel risk markers (based on the following) and clinical outcome. Secondary:Developing a score from the predictive model that can be used to assess risk given a patient*s combination of risk factors.
The primary objective is to evaluate the difference in 68Ga-exendin tracer accumulation in the pancreas of patients with and without complete resolution of T2DM after RYGB by quantitative analysis of PET images.
In 2009, a new combination of MRI sequences was published by Deoni et al. (2009) that promised the ability to measure the myelin water in vivo over the whole head in a clinically useful time. Referred to as mcDespot (multi-component driven…
The primary aim of this study is to validate a screening instrument for ophthalmologic disorders using full, in depth ophthalmologic assessment as the gold standard. Secondary aims include:* To study the severity and clinical impact of different…
The main objective is to examine the change in 68Ga-exendin tracer accumulation in the pancreas (i.e. beta cell mass) after RYGB by quantitative analysis of PET images before and one year after RYGB in morbid obese patients with type 2 diabetes.
The focus of this study is to get more insight in the pathophysiology of IUGR. The main goal is to investigate the applicability of STIC in determining fetal cardiac function in IUGR.
The key objectives of this study are:1. To determine by means of IENFD whether the PNS is involved in patients with autonomic complaints in MS. The obtained IENFD values will be compared with the age and gender matched healthy normative data,…
1. To evaluate the clinical usefulness of STIC with post-process rendering capability. Our goal is to investigate whether STIC gives more accurate information about a suspected cardiac anomaly, compared to conventional 2D ultracardiography.2. To…
We will investigate the feasibility of using STIC technology to evaluate the normal fetal cardiac anatomy and morphology in different stages of gestation. Further we aim at making normograms of different intracardiac parameters in relation to…