273 results
To further optimize 7.0 Tesla MRI techniques and to develop new MRI techniques that will enable state-of-the-art clinical and cognitive research leading to improved patient care. Whereas some applications of 7.0 Tesla MRI already show improvements…
The development of a valid and reliable test intended to measure functional motor activities in daily life of children with DCD.
The aim of this study is assessment of right ventricular function: a comparison between MRI and real-time 3-D echocardiography (RT 3-D echo). We have the following research questions: 1) Is assessment of right ventricular (RV) function with RT 3-D…
This study wants to evaluate on intraoperative MRI whether contrast enhancement at the borders of the resection cavity correlates with tumor tissue, and whether no contrast enhancement correlates with the absence of tumor tissue. To differentiate…
Primary: To investigate whether high-resolution MRI, 18F-FDG PET, and microemboli detection, or a combination of these techniques, enable to identify patients in the 30-69% stenosis group with an increased stroke risk. Secondary: To compare the…
Evaluation and comparison of sentinel node biopsy (SNB) and ultrasound guided fine needle aspiration cytology (USgFNAC) in the management of the clinically negative neck in patients planned for transoral excision of oral and oropharyngeal squamous…
Evaluation of the diagnostic value of stomach and small bowel mucosal oxygen saturation measurements in patients suspected for chronic gastrointestinal ischemia.Determination of normal mucosal oxygen saturation values in patients without chronic…
The project has the following objectives:1. To investigate the diagnostic value of beta amyloid oligomers in CSF and plasma for AD in subjects with mild dementia. 2. To investigate whether beta amyloid oligomers in CSF and plasma can predict AD in…
Primary Objectives:- To investigate the effects of a single dose (plasma concentration) 5-HTP challenge test (5-HTP200mg/CBD100+50mg/granisetron2mg) on hypothalamic fMRS activation patterns in healthy male volunteers.Secondary Objectives:- To assess…
The objective of the standardized protocol is optimalizing the accuracy of the diagnosis (all-cause pneumonia, or serotype-specific pneumonia) during the 13-valent pneumococcal vaccin (13vPnC) study which will be performed in 2008. Additionaly, the…
The study will be divided into two projects: Reproducibility study: To assess reproducibility of analysis of EBC by means of Orbitrap MS, in asthmatic children, with and without atopy.Correlation study: To correlate the results of Orbitrap MS…
The primary objective of this study is to evaluate whether treatment with nesiritide improves patient outcomes (as measured by reduction in the composite of HF rehospitalization and all-cause mortality through 30 days after randomization [Day 30])…
Primary objective is to investigate the feasibility of Hexvix® blue light URS. Secondary objectives are to determine the diagnostic value of Hexvix® blue light URS as compared to digital and fiberoptic white light URS, and to assess safety and…
To determine the diagnostic accuracy of FDG-PET-CT (pre-treatment and in the early phase of treatment) in the prediction of local control after primary radiotherapy with or without chemotherapy for functionally inoperable HNSCC.
Assessing hereditary and aquired determinants of ETP. Evaluating the use of ETP as predictive stand alone test for recurrent DVT and bleeding complications due to anticoagulation therapy in comparisson with the current prediction methods.
1-objective: to get insight in objective (urodynamic) and subjective (questionnaire) changes of the lower urinary tract after laparoscopic robot assisted radical prostatectomy, Intensity modulated radiotherapy, I-125 brachytherapy.2-To create…
The primary aim of this MAPCAT-study is to investigate whether pharmacokinetics of clopidogrel differ significantly betwen different clinical scenarios. A second aim is to study specifically whether genetic polymorfisms influence these…
The main objectives of this study are to describe behavioural problems in children aged 0 to 4 years and posttraumatic stress symptoms in children aged 8 to 17 years and to study the course and determinants of these problems. Further, this study…
Primary objectives:1) Describe the PD effects on plasma ACTH and serum cortisol upon 100 µg hCRH injection with or without a preceding injection of 10 µg dDAVP 2 hours earlier and study the PK-PD relationship (*Block B*). In particular, the outcome…