261 results
We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…
To establish the diagnostisch accuracy of ultrasound for the exclusion of fracture of the elbow
The current study aims to elucidate neural correlates of pain processing and dissociative analgesia in PTSD. To this end, we want to replicate the pilot study by Mickleborough et al., (2011) and test the functional pain processing protocol with…
The primary objective of the study is to compare the ADR between PCSC and CC in patients referred for diagnostic, screening (non-iFOBT based) or surveillance colonoscopy.Secondary objectives are the following:- To compare the polyp detection rate (…
To establish a point prevalence of asymptomatic proximal lower extremity DVT in patients admitted to the ward with COVID-19.
The primary objective of this study is to demonstrate that our DLA-based method is promising enough to detect CTCs in ER+, N+ primary breast cancer patients after 5 years ET. Simultaneously, other methods (CTC detection in 7.5 ml and 30 ml of blood…
The primary objective of this project is to investigate whether using prognostic factors from the PD, NP and PP domain will lead to a better prediction of treatment outcome in veterans with PTSD. Our secondary objective is to investigate whether the…
The primary objective of this study is to assess the diagnostic accuracy, in terms of sensitivity and negative predictive value, of preoperative CT lymphography as compared with conventional lymphoscintigraphy for SLN detection. Secondly, we aim to…
Primary Objectives: To evaluate the status of the circadian rhythm of critically ill children in multiple facets and on multiple moments during their PICU stay. To describe the distributions of rhythmic parameters in the paediatric ICU and their…
- special attention for the development and harmonization of the pre-analysis of liquid biopsy, for blood as well as urine, and next to this for ctDNA as well as ctRNA- special attention for the detection of AR-V7 in blood and urine- special…
The current research is focused on finding a method that is able to better stratify the patients. A possible method could be to study PSA in more detail, specifically the modifications which are present on the protein. One of these modifications is…
The aim of the current study is to examine whether it is possible to improve speech recognition in specific CI users by optimizing dynamic range and mean aided thresholds. Furthermore, we want to investigate to what extent patient counselling and…
2.1 Primary ObjectiveDescribing the association between Handscan optical scores, markers of inflammation (levels of CRP, serum IL-6) and clinical swollen joint score in three treatment groups with different pharmacokinetic modes of action for RA…
To determine the accuracy and acceptability of a minimal-invasive screening strategy (breath testing (eNose) followed by unsedated transnasal endoscopy (uTNE)) for Barrett*s esophagus (BE) and esophageal adenocarcinoma (EAC).
The primary objective is to evaluate the uptake, including the distribution, of [68Ga]Ga-PSMA-11 in enhancing glioma and brain metastases eligible for (re-)resection by performing [68Ga]Ga-PSMA-11 PET/MRI scans, in order to study the potential of…
Assessment of the detection of neoplastic lesions in patients with longstanding inflammatory bowel disease, using different endoscopic imaging techniques. Colonoscopy will be performed with either A) HDWLE, B) back-to-back HDWLE or C) CE.
1. To report the natural history of retinal degeneration in patients with biallelic mutations in the EYS gene.2. To identify sensitive structural and functional outcome measures to use for future multicenter clinical trials in EYS-related retinal…
Primary Objective: The aim of the present study is to find which point-of-care test (ACT or aPTT) is superior in predicting bleeding complications within 24h after both TAVI (Cohort A) and CTO PCI (Cohort B) procedure. Secondary Objective(s): The…
This study aims to investigate the feasibility and clinical performance of tissue perfusion imaging with MSOT in the lower extremity of healthy volunteers, claudicants and patients with critical limb-threatening ischemia. The main objective is to…