306 results
The aim of this study is to develop a safe and fast MRI protocol for the imaging of neonatal and pediatric BPD patients. This METC application addresses the first part of the MRI- BPD project: *Ventilation, Inflammation, perfusion and structure in…
The purpose of the Confirm RxTM SMART Registry is to collect real world data to assess the safety and performance of the Confirm RxTM Insertable Cardiac Monitor (ICM) and system over a 12 month period.
The main goal of this technical feasibility study is to investigate with which HPV isolation and detection method urine and the Evalyn Brush can be combined. HPV stability in urine and on the Evalyn Brush will be investigated as it*s unclear how…
Evaluation of the feasibility of the combination of (DW-)MRI and digital FDG-PET/CT for prediction of response to chemoradiation therapy.
To identify local flow patterns that can predict disease progression and failure of stent patency in patients with untreated and treated atherosclerotic lesions in the aortoiliac tract.
The primary objective of this study is to determine the safety and feasibility of fluorescence molecular endoscopy using the fluorescent tracer bevacizumab-800CW for identification of pathological complete response after neoadjuvant…
The primary objective is to quantify the degree of shoulder instability by determining the contact surface area between the glenoid and the humerus together with the translation of the humeral head during motion using three-dimensional CT scanning.…
The aim of the present study is to optimize treatment selection by examining patient characteristics that predict (differential) treatment response across DBT and ST. These characteristics will be investigated and converted to actuarial formulas (…
The aim is to see whether intradialytic parenteral nutrition is an efective treatment against the loss of muscle mass
Neuroplast has scheduled to start in 2018 with a phase I and a phase II/III clinical trial with patients with a traumatic spinal cord injury to confirm the efficacy and safety in humans. A GMP license to produce clinical grade Neuro-Cells is…
Primary objective:To compose multifaceted predictive signatures for PD-1 or anti-PD-L1 antibody effects with relevant components of integrative omics (histology, immunohistochemistry, genomics, transcriptomics, proteomics, radiomics and molecular…
The overall aim of the current study is to investigate the efficacy of a novel, accessible, transdiagnostic ecological momentary intervention for improving self-esteem (*SELFIE*) and examine underlying epigenetic mechanisms in youth with prior…
The aim of this study is to combine measurements of the NDT with EEG recording and analysis to observe neurophysiological activity during nociceptive processing in CRPS patients. In this explorative study, multiple types of stimuli are delivered.…
The primary objective is to assess diagnostic accuracy of MRDTI/BTI for first and recurrent CVT in patients referred for MRI/MRV in the setting of routine clinical setting. The secondary objectives are to optimize MRDTI/BTI sequences for imaging…
Our primary objective is to prospectively implement and validate the YEARS strategy in primary care. Secondary objectives are, (i) to quantify the added diagnostic value of C-reactive protein (CRP) to a clinical assessment and D-dimer testing in…
Objective: To assess whether early changes in hypoxia between baseline and in the (end of the) second week of proton therapy are predictive for time-to-local recurrence in patients with HNSCC (primary). Secondary objectives include: to compare the…
To evaluate the effectiveness and cost-effectiveness of intensive GDM treatment as compared to routine maternity care in pregnant women with a discordant OGTT result between the new (2013) WHO criteria as compared to the old (1999) WHO criteria for…
The study objective is to compare the pituitary uptake of 68Ga-NODAGA-exendin in patients with and without adequate response (based on HbA1c or weight loss or classification by the treating diabetologist) to GLP-1R agonist treatment, to increase…
To assess platelet function and coagulation parameters in adult chronic ITP patients in relation to their bleeding phenotype
The influence of mobilisation of the sacroiliacal joint and an stabilizing or relaxation exercise program on pain, the function of the pelvic floor, the m. Transversus Abdominus and functional state in patients with pelvic girdle pain.