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Management of Atrial fibriLLation INcluding tailoring of anticoagulation in patients from primary care - ALL-IN

To evaluate whether integral AF treatment in primary care is non-inferior in terms of reducing all-cause mortality (primary outcome) and specific cardiac mortality and hospitalization and non-cardiac hospitalization (secondary outcomes), as compared…

Sexual Health and Relationship Enhancement of patients with Prostate Cancer and their partners

This study is designed in order to determine the type and timing of sexual rehabilitation after prostate cancer treatment according to the patient*s and the patient*s partner*s point of view. Furthermore, it will assess which health care provider…

Physical and psychological sequelae of childhood cancer from diagnosis till 5-8 years after diagnosis

The current study is a continuation of the cohort 5-8 years post-diagnosis and aims to evaluate:1.The course of the nutritional status, and the related factors and consequences of malnutrition in survivors of childhood cancer until 5-8 years post-…

GOLD D in primary care: a group whose clinical outcomes can easily be improved

The aim of the current study is evaluation of the Certe A/C service system. This is achieved via 2 workpackages:Workpackage 1 constitutes of describing patient characteristics (age, gender, current medication, smoking status and comorbidities) of…

HbA1c lowering before surgery in poorly controlled diabetes mellitus; a pilot study

to study the feasibility of lowering HbA1c before elective surgery in patients with suboptimalpoorly controlled DM (HbA1c >7%/53 mmol/mol).

ENdometrial cancer SURvivors' follow-up carE (ENSURE): Less is more? Randomized controlled trial to evaluate patient satisfaction and cost-effectiveness of a reduced follow-up schedule

The aim of this study is to compare a reduced follow-up schedule of 4 visits among low-risk, early-stage endometrial cancer survivors, with the schedule according to the current Dutch guideline that includes 10 to 13 visits, on:Primary outcomes:1.…

The effects and costs of a multidisciplinary symptomatic treatment strategy on quality of life of people severely affected by MS

The aim of the proposed study is to obtain insight into the needs, functioning and quality of life and changes in these outcomes of people with severe MS who are treated in NU and to identify the experiences, facilitators and barriers using the…

CHOICE: CHOosing treatment together In Cancer at the End of life

We aim to test the effectiveness of a patient-targeted preparatory tool (*Gesprekswijzer*) and an oncologist-targeted communication skills training to enhance shared decision making in consultations about palliative systemic treatment. The primary…

The SO-HIP study,
Effectiveness of sensor monitoring in an occupational therapy rehabilitation program for older persons after hip fracture: design of a three-arm stepped wedge cluster randomized trial

The primary objective is to study the effect of sensor monitoring embedded in an OT rehabilitation program for older persons after hip fracture on recovery of daily functioning, 6 months after the start of rehabilitation, as compared to coaching by…

HOMERUN
Initiation of HOme MEchanical ventilation at home in a selective group of patients with chronic hypercapnic Respiratory failUre in the Netherlands

Patients with chronic respiratory failure currently start their ventilatory support in hospital as stated in national guideline. However, as these patients are severely disabled, a stay at the hospital for several days is experienced by many as very…

Effictiveness of the online self management training Reuma Uitgedaagd! for adults with a rheumatic disease

The objective is to study the effectiveness of the online self management training Reuma Uitgedaagd! voor adults with a rheumatic disease.

A decision model for the management of acute exacerbation chronic obstructive pulmonary disease in the emergency department: flowchart for treatment allocation.

The primary objective is to validate a previously established prognostic instrument in the form of an algorithm (flowchart) in patients that present with AECOPD to the department of emergency medicine for classifying for out- or inpatient treatment…

An explorative study to assess the potential impact of the Incosense Smart in Envida

The aim of this study is to explore the potential impact of the Incosense Smart at the client, professional, care processes and organization.

Palliative care for people with addiction and multiple problems: an explorative study of problems, needs, improvements and good examples experienced by healthcare professionals, patients and proxies.

The main question of this study is: "how is palliative care for people with addiction and multiple problems organized in the Netherlands, and which problems, needs, improvements and good examples are experienced by healthcare professionals,…

CRP-POCT in suspected airway infected patients in the long-term care facility

The main objective is to investigate the additional value of CRP-POCT (C-reactive protein point-of-care-test) testing in patients suspected of airway infections in long-term care facilities.

ACS Prototype for 'post-discharge self-management'- proposition for patients, medical staff and care institution.

To gain qualitative insights into the value of the *ACS post-discharge self-management proposition* for patients, medical staff and care institution. Understand how this prototype is used in practice by patients and staff * Investigate how it…

Validation of the Sustained Attention to Response Task (SART) for assessing the fitness to drive in narcolepsy and idiopathic hypersomnia patients

Primary aim is to validate the SART as a screenings instrument for driver fitness in patients with narcolepsy and idiopathic hypersomnia.

Closing the preventive care chain for overweight children: evaluation of the implementation of an integrated, locally aligned approach, enforcing primary care.

Get insight in the implementation and effectiveness of the integrated preventive care chain for overweight children in 's-Hertogenbosch. With the results we can optimize the support for overweight children and their parents. .

Systemic sclerosis: CT-derived evaluation of interstitial lung disease and pulmonary vasculopathy for assessment of progression of disease.
Research protocol for extended volume HRCT-thorax in patients with systemic sclerosis participating in a 2 *day multidisciplinary team care program of the department of Rheumatology and Pulmonology

zie nederlandse samenvatting

A prospective multicenter cohort study to evaluate the benefit of the geriatric fracture center (GFC) concept * Evaluation of a geriatric co-management program

To investigate the effect of a GFC regarding major adverse events (AE) with a relationship to the treatment / residential status / immobilization (as defined under "Primary outcome measures") from surgery to a 36 month follow-up.