246 results
Objective: Our general objective is to investigate the neurobiological substrates of a broader ADHD phenotype.
Investigate the incidence and severity of early coagulopathy in severe sepsis and septic shock patients and investigate the correlation between these coagulation disturbances and the incidence and severity of microvascular changes.
The primary objective to our study is assessing functional outcome, quality of life, and genetic mutations in patients with a cloacal malformation. Functional outcome:- Colorectal functiono Objective: assessing colorectal function through the use of…
This study has two main objectives. One objective is to investigate which cognitive and affective mechanisms can be influenced through treatment which leads to improved social functioning. We will use a carefully selected set of behavioral,…
The primary aim of this observational study is to determine the occurrence of exercise-induced left ventricular diastolic dysfunction (LV-DD) in symptomatic COPD patients with a normal echocardiography at rest. And, secondly, to study the…
We try to find a new standard within the field of ''MicroRNA'' proteins, that swim around in peoples blood and/or urine. MicroRNA's are very small proteins, that switches of genes in the cells, they are able to switch genes…
The aim of the present study is to increase our understanding of the cost effectivity and the pathophysiology underlying the beneficial effect of autologous SCT. We will investigate the immunological mechanisms involved in the (re)induction of…
The aim of the vaginal morbidity sub-study is to better understand the different physical, dosimetric, biological, clinical and psychological factors and to analyse the importance of these factors for patient reported outcome on sexual functioning…
To assess renal sympathetic reinnervation in the kidney allograft by 123-I-MIBG scintigraphy.
To determine the frequency of MBL and FCN SNPs in patients with a history of a proven gram-positive bacteremia, compared to patients without such history. A secondary objective is to determine whether extracorporeal circuits, used in cardiothoracic…
In this study we aim to investigate whether infusion of intestinal microbiota from lean (vegetarian) donors has differential effect on choline (d6-labeled choline) and carnitine (d3-labeled carnitine) metabolism and macrovascular inflammation (18F-…
The purpose of this study is to make it possible to make a prediction of risk of amputation stump wound healing without the need for re-intervention and whether a secondary amputation.
Primary Objective: To study changes of T cell subsets (Th1/Tc1, Th2/Tc2, Th17/Tc17, regulatory T cells and senescent T cells) in healthy ageing and unhealthy ageing. Secondary Objective(s): - To study the immune risk phenotype in healthy persons…
To identify risk factors for injuries in novice runners, and to identify risk factors for specific injuries.Secondary Objective(s): 1. To determine the incidence of running related injuries in novice runners2. To describe the health benefits of the…
The following research questions were formulated:• Does blood group P status (presence or absence of the 42C>T-SNP) correlate to GB3 content on fibroblasts and white blood cells of healthy controls?• Does blood group P status correlate to (…
1) To investigate the differences in lipid content of the plaques after placement of a Stentys self-apposing stent. 2) To investigate whether there is a correlation between the decrease lpid-core content and the increase in cardiac biomarkers (…
To detect the differences in the length of the urethra in healthy volunteers and in men after laparoscopic radical prostatectomy.To detect the degree of erectiel dysfunction before and after laparoscopic radical prostatectomy.To detect the cause of…
Primary Objective: Using task fMRI to assess differences in the brain activation during evaluative social feedback and script-driven emotional imagination between participants with BPD and healthy controls. Moment-to-moment self-esteem and mood…
To determine the direct effects of morning light intensity on postprandial glucose and lipid metabolism and metabolic gene expression in adipose tissue.
Main Objective: - to validate the identified cognitive profiles prospectively in a new population using confirmatory cluster analysisSecondary Objectives: - to identify the clinical and demographical factors associated to the identified cognitive…