78 results
The present study will focus on the consequences of long-term delay of puberty induced by treatment with Decapeptyl-CR. We will investigate the effects of this treatment in regard to brain functioning, brain development, various endocrine, metabolic…
To examine the effect of surgical trauma on mucosal perfusion, intestinal epithelial damage, the inflammatory response and potentially sepsis, following surgery remote to the abdomen in adults, children and neonates,
Using pedigree research in two CVID-families to find clues for genetic testing.
The main objective of this research proposal is to 1). develop an on-line monitor for young athletes to prevent them from a systematic overload and to avoid overtraining 2) develop clinical tools to improve diagnostics of overtraining.
To what extent does the resistance to stretch of spastic muscles differ from that of non-spastic ones?Does tendon transfer affect a muscle*s functional capacity?
This study will assess both implicit and explicit effect expectancies associated with marijuana in individuals with psychotic disorder. We will determine whether such expectancies are different from those of people in the general population. We will…
To perform a genetic study of left-handedness and language lateralization as endophenotypes of schizophrenia. The study will make use of 30 extended multigenerational pedigrees with multiple left-handers from Urk, an isolated population in The…
The objective of the study is to assess whether in young patients with arteriopathic stroke perfusion abnormalities in non-infarcted brain are associated with the type and course of arteriopathy and stroke outcome in terms of functional recovery and…
Cognitive processes and the development of psychopathology in children at risk for anxiety disorders
Goal of the study is to establish evidence on cognitive biases in a high risk population and on the longitudinal impact of such biases. We hypothesize that CPAD*s show biases in their information processing when compared to control children. We…
To develop and validate a biomechanical measurement protocol that can assess wrist flexion deformity resulting from a UMN lesion.
Analyze the correlation between change in EELV with change in MIF¬50
Identification of genes that are involved in congenital heart defects.
To identify novel childhood cancer-predisposing genes in children.
To investigate the onset and short term natural course of ADD and TMJ hypermobility in children, and to give insight into some related risk factors.
Assembly of a large sample of patients/families with nonsyndromic oro-facial clefts from Central Europe for identification of genetic factors responsible for this phenotype by usage of association and linkage disequilibrium studies.
The major aim of this project is to elucidate the molecular basis of IgAN. A large cohort of IgAN patients will be screened on aberrancies in the DNA sequence or expression of the gene encoding Cosmc, a protein that is essential for the biosynthesis…
1. To study the possible association between MBL-deficiency and the occurence and severity of infections in MBL-deficient CF patients.2. To study the possible association between MBL-deficiency and the severity of cystic fibrosis.3. To study the…
This study observes the immune system of children and adults who have been without a thymus for 3 to 30 years. Our objective is to study the role of the thymus in the developing immune system. In addition this study will give insight in the long…
The main objective of this research proposal is to 1). the devolpment of a monitor with stress and recovery parameters to predict long-term performance decrement in young elite athletes2). evaluating the association between endocrinological and…
The primary oblective of the study is to elucidate all molecular mechanisms leading to coeliac disease.In order to establish the scientific basis for the development of improved diagnostics, novel therapies and safer foods for patients, in the CDC:…