3877 results
Primary Objective: To determine the differences in function and morphology of the distinct abdominal adipose tissue depots (e.g. SAT, PVAT, OAT and MAT; see figure 1) in patients undergoing elective open abdominal aortic surgery.Secondary…
PROVALID will have 3 major objectives:Primary: Determine the cumulative incidence of renal outcomes in patients with type II diabetes in different European countries. Renal outcomes are defined as:* Progression from normoalbuminuria to…
Our primary objective is to determine the effect of breast reconstruction on the risk of developing lymphedema. Secondarily, we will look at lymphedema and the correlation with 1) primary and secondary breast reconstruction, 2) the extent of…
Objective: The primary objective is to determine if the dietary fructan-fiber inulin is applicable in PPIH. More specific, it aims to (i) improve the magnesium balance in cases of hypomagnesemic PPI users and (ii) to evaluate if the use of inulin is…
The primary objective of this study is to examine whether people with autism have an atypical sensitivity to specific visual information, and if this can explain differences between them and healthy controls in looking at faces.
The first goal of the present study is to elucidate the network topology of the MTL on both large-scale and micro-scale levels with the aim of further understanding epilepsy related changes to the network structure. Additionally we will also use the…
Objectives: 1. To investigate the types of antitrombin deficiency in these families2. To find the mutations in our families/patients with antitrombin deficiency.3. To establish the risk of VTE due to these mutations and subtypes.(comparing…
(this text is taken from the protocol, see protocol for the detailed version)The main objective of the study is to gain insight in the underlying mechanism of tinnitus suppression. This objective will be achieved by comparing the suppressive effect…
To evaluate the prevalence of gastrointestinal ischemia in patients with acute and chronic non-cirrhotic, non-malignant PVT.
The characterization of T cells that reside in kidney transplants.The characterization of the T cell-mediated antiviral responses in kidneysThe role of kidney-resident T cells in acute and chronic allograft rejection
To identify risk factors for injuries in novice runners, and to identify risk factors for specific injuries.Secondary Objective(s): 1. To determine the incidence of running related injuries in novice runners2. To describe the health benefits of the…
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
Identification of the proteins that are involved in neurite outgrowth in PDR. We want to determine what protein levels are increased in the vitreous by local production and which RNA transcripts are present in the fibrotic membranes of patients with…
The proposed longitudinal study aims to examine1) if the onset of type 1 diabetes before vs. during puberty results in different outcomes of glycaemic control, self management, psychological functioning and diabetes-related QoL2) how the development…
The aim of the vaginal morbidity sub-study is to better understand the different physical, dosimetric, biological, clinical and psychological factors and to analyse the importance of these factors for patient reported outcome on sexual functioning…
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
The primary aim of this study is to validate the paradigms designed to investigate the effects of social stress and reward on in healthy individuals. This will allow us to evaluate and optimize the experimental paradigms in terms of their design,…
Primary objective:To assess the two-year prevalence and incidence of clinical relevant arrhythmias in drug-resistant epilepsy.Secondary objective:To assess whether the recorded cardiac arrhythmias are related to epileptic seizures (subjectively from…
Primary Objective: To identify variants in the humane genome that are associated with BE risk. Secondary Objective(s): We will collect information on BE length, complication of BE (dysplasia, ulcer, stricture or EAC), presence of esophagitis and…
In one FOA family we have detected a deleterious mutation in a compelling gene which co-segregates with the FOA phenotype in the family. This mutation is, therefore, is likely to be causal to the early onset OA. The objective of the study is:a) To…